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Record W4411745691 · doi:10.1002/mus.28463

Idiopathic Inflammatory Myopathies and Malignancy Screening: A Survey of Current Practices Amongst Canadian Neurologists and Rheumatologists

2025· article· en· W4411745691 on OpenAlexafffundabout
Maria Jekielek, Rosane Nisenbaum, Ophir Vinik, Charles D. Kassardjian

Bibliographic record

VenueMuscle & Nerve · 2025
Typearticle
Languageen
FieldMedicine
TopicInflammatory Myopathies and Dermatomyositis
Canadian institutionsSt. Michael's HospitalPublic Health OntarioUniversity of Toronto
FundersUniversity of Toronto
KeywordsMalignancyMedicineInternal medicinePhysical therapy

Abstract

fetched live from OpenAlex

INTRODUCTION/AIMS: Although the need for malignancy screening in idiopathic inflammatory myopathies (IIM) is generally accepted, data to guide the choice and timing of investigations are limited. Our aim was to characterize the gaps and uncertainties amongst Canadian neurologists and rheumatologists with respect to malignancy screening in IIM. METHODS: An online survey consisting of 18 multiple-choice questions related to malignancy screening practices was distributed to adult neurologists and rheumatologists practising in Canada, and survey responses were described and compared between groups. RESULTS: Of 69 participants, the majority (95.7%) performed malignancy screening. However, there was variability in practice including delegation and choice of screening tests, influence of patient-specific factors, and timing of repeat testing relative to original testing. Only 18.2% of respondents were confident in their malignancy screening practices. The most significant perceived knowledge gap was lack of consensus or guidelines on choice and frequency of malignancy screening (92.8%). Compared with neurologists, rheumatologists saw a higher number of IIM patients per year (72.5% vs. 41.4% reported five or more, p = 0.009), were more likely to consider patient risk factors and order more investigations, while neurologists were more likely to repeat testing. DISCUSSION: Variability and knowledge gaps exist amongst neurologists and rheumatologists with regard to malignancy screening in IIM patients. The identified variability and lack of confidence may lead to lack of standardization of care, and potentially either under- or over-investigating of IIM patients for malignancy. Further research is required to better understand the optimal choice of tests and timing of repeat investigations.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.017
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.301
Teacher spread0.265 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes3
Has abstractyes

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