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Record W4411786789 · doi:10.1093/ije/dyaf113

School opening associated with lower test-adjusted COVID-19 case rates in children

2025· article· en· W4411786789 on OpenAlexaff
Ambarish Chandra, Tracy Beth Høeg

Bibliographic record

VenueInternational Journal of Epidemiology · 2025
Typearticle
Languageen
FieldMathematics
TopicCOVID-19 epidemiological studies
Canadian institutionsThe Scarborough HospitalUniversity of Toronto
Fundersnot available
KeywordsMedicineConfoundingDemographyObservational studyPopulationEpidemiologyCoronavirus disease 2019 (COVID-19)PediatricsTest (biology)Environmental healthDiseaseInfectious disease (medical specialty)

Abstract

fetched live from OpenAlex

BACKGROUND: There is conflicting evidence from prior studies on the relationship between in-person schooling and transmission of SARS-CoV-2 among children. This may be due to multiple confounders in estimating this relationship, including the decision to close schools, community rates of infection, and rates of testing. METHODS: Regression-based observational study to estimate the relationship between school openings and COVID-19 case rates among children, while accounting for potential confounders including community case rates, mitigations in schools, and rates of testing among schoolchildren. The setting is US school districts in the Fall of 2021, from 3 weeks prior through 12 weeks after school opening, using restricted data obtained from the Centers for Disease Control and Prevention. Data were available for school districts in 2592 counties, containing 86% of the US population. RESULTS: School openings were associated with a brief rise in cases among children relative to adults, with a peak of 39.3 [37.7, 40.9] additional cases per 100 000 per week. However, children were tested at higher rates when schools were in session. After adjusting for testing rates, case rates among children were significantly lower after schools reopened by 4.7 cases per 100 000 compared with over summer break. CONCLUSION: School reopening in the USA in the 2021-22 academic year was accompanied by an increase in SARS-CoV-2 testing in children and a brief rise in pediatric cases. When testing rates are accounted for, school reopening was associated with a decrease in COVID-19 cases among children relative to adults. A lower threshold for testing in the school setting may be an important confounder in studies of SARS-CoV-2 transmission.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.017
Threshold uncertainty score0.034

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.006
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.210
GPT teacher head0.483
Teacher spread0.273 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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