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Gender-based analysis of WOMAC scores in moderate and advanced knee osteoarthritis: evaluating pain, stiffness and functional impairment

2025· article· en· W4411793338 on OpenAlexaboutno aff
Aavrati Rastogi, Roop Bhushan Kalia, Pradeep Meena

Bibliographic record

VenueInternational Journal of Community Medicine and Public Health · 2025
Typearticle
Languageen
FieldMedicine
TopicOsteoarthritis Treatment and Mechanisms
Canadian institutionsnot available
Fundersnot available
KeywordsWOMACOsteoarthritisFunctional impairmentMedicinePhysical therapyPhysical medicine and rehabilitationKnee painInternal medicineAlternative medicinePathology

Abstract

fetched live from OpenAlex

Background: Knee osteoarthritis (KOA) significantly impacts mobility and quality of life, with key issues being pain, stiffness, and functional restrictions. With possible differences in the course of the disease and the intensity of symptoms, gender differences in OA symptoms are still uncertain. Using the Western Ontario and McMaster Universities Arthritis Index (WOMAC), this study examined gender-based variations in the burden of OA symptoms between KL grade 2 and KL grade 3 KOA. Methods: According to the EULAR classification, 108 patients with KOA were included in the study. Male and female patients with knee OA underwent WOMAC scores for pain, stiffness, function, and overall discomfort examined. Statistical significance was evaluated using 95% CI, mean differences, and independent t-tests. A p value of less than 0.05 has been considered significant. Results: Across all WOMAC domains, no statistically significant gender differences were discovered, and all comparisons had p values greater than 0.05. In KL grade II, males scored slightly higher on pain and stiffness, but in Kl grade III, these differences decreased. In both grades, the functional and total WOMAC scores were similar for both genders. Conclusions: The results show that among those with knee OA, there are no appreciable differences in symptom load by gender. This highlights the necessity of tailored treatment plans as opposed to gender-specific approaches. Other factors affecting OA outcomes, such as biomechanics, hormonal effects, and lifestyle factors, should be investigated further.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.934
Threshold uncertainty score0.408

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.086
GPT teacher head0.387
Teacher spread0.301 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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