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Record W4411849935 · doi:10.1038/s41598-025-08313-7

Associations of water intake and Intra-Meal fluid consumption with obesity, insulin resistance, and predictors of cardiovascular diseases among Iranian women

2025· article· en· W4411849935 on OpenAlexaff
Hanieh Moosavi, Elnaz Daneshzad, Mohammad Matin Mahjourian, Nick Bellissimo, Leila Azadbakht

Bibliographic record

VenueScientific Reports · 2025
Typearticle
Languageen
FieldMedicine
TopicDiet and metabolism studies
Canadian institutionsToronto Metropolitan University
FundersTehran University of Medical Sciences and Health Services
KeywordsInsulin resistanceObesityMealMedicineWater consumptionInsulinInternal medicineConsumption (sociology)EndocrinologyEnvironmental healthEnvironmental science

Abstract

fetched live from OpenAlex

To evaluate the associations of water intake and Intra-Meal Fluid Consumption with obesity, insulin resistance, and predictors of cardiovascular diseases. A cross-sectional study was conducted with 371 women aged 20-50 years in Iran. Physical activity, biochemical, and anthropometric measurements were collected. Dietary intake was collected using a 168-item food frequency questionnaire. Water intake was assessed through three non-consecutive 24-hour dietary recalls, and participants were classified into water intake tertiles, T1 (< 1.5 L/day), T2 (1.5-2.0 L/day), and T3 (> 2 L/day) based on recommended intake levels from the Institute of Medicine. Triglyceride and glucose (TyG) index, lipid accumulation product (LAP) index, Castelli risk indices 1 and 2 (CRI-I and CRI-II), atherogenic index of plasma (AIP), and hypertriglyceridemic waist phenotype were used as predictors of cardiovascular diseases. Women in the second and third tertiles of water intake had significantly lower body weight, BMI, waist circumference, fasting blood glucose, and triglyceride levels compared to those in the lowest tertile (p < 0.05). Higher water intake was also associated with lower odds of TyG index (OR:0.51; 95%CI:0.32,0.81; p = 0.005), LAP index (OR:0.35; 95%CI:0.22,0.56; p < 0.001), CRI-I (OR:0.57, 95%CI:0.33,0.96; p = 0.031), AIP (OR:0.57; 95%CI: 0.36,0.91; p = 0.017), and hypertriglyceridemic waist phenotype (OR:0.20; 95%CI:0.12,0.34; p < 0.001). Higher water intake may be associated with lower odds of obesity, fasting blood glucose, and predictors of cardiovascular disease in Iranian women.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.222
Teacher spread0.214 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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