Evaluating ChatGPT and DeepSeek in postdural puncture headache management: a comparative study with international consensus guidelines
Bibliographic record
Abstract
OBJECTIVE: To evaluate the use of ChatGPT and DeepSeek in clinical practice to provide healthcare professionals with accurate information on the prevention, diagnosis, and management of post-dural puncture headache (PDPH), in particular to evaluate ChatGPT-4o, ChatGPT-4o mini, DeepSeek-V3 and DeepSeek with Deep Think(R1)'s responses with consensus practice guidelines for headache after dural puncture. BACKGROUND: Post-dural puncture headache (PDPH) is a common complication of dural puncture. Currently, there is a lack of evidence-based guidance on the prevention, diagnosis and management of PDPH. The 2023 Consensus guidelines provide comprehensive information. With the development and popularization of AI, more and more people are using ai models, including patients and doctors. However, the quality of the answers provided by ai has not yet been tested. METHODS: Responses from ChatGPT-4o, ChatGPT-4o mini, DeepSeek-V3, and DeepSeek-R1 were evaluated against PDPH guidelines using four dimensions: Accuracy (guideline adherence), Overconclusiveness (unjustified recommendations), Supplementary information (additional relevant details), and Incompleteness (omission of critical guidelines). A 5-point Likert scale further assessed response accuracy and completeness. RESULTS: All four models show high accuracy and completeness.Of the 10 clinical guidelines evaluated,ChatGPT-4o, ChatGPT-4o mini, DeepSeek-V3 and DeepSeek-R1 all showed 100% accuracy in responses (10/10)(p = 1). None of the four models showed overly conclusive results(p = 1). In terms of supplementary information, ChatGPT-4o,ChatGPT-4o mini and DeepSeek-R1 are 100% (10/10), DeepSeek-V3 is 90% (9/10)(p = 1). In terms of incompleteness, ChatGPT-4o is 80%(8/10), DeepSeek-R1 is 70%(7/10), ChatGPT-4o mini and DeepSeek-V3 are 60% (6/10) (p = 0.729). CONCLUSION: All four AI models demonstrate clinical validity, with ChatGPT-4o and DeepSeek-R1 showing stronger guideline alignment. Though largely accurate, their responses achieve only 60-80% completeness relative to medical guidelines. Healthcare professionals must exercise caution when using AI tools and should critically evaluate outputs before clinical application. While promising, their partial guideline coverage requires careful human oversight. Further validation research is essential before these models can reliably support clinical decision-making for complex conditions like PDPH.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".