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Record W4411947172 · doi:10.3138/cjgim.2024.0033

Physiologic changes in normal pregnancy: A systems-based approach with clinical tips for the consultant

2025· article· en· W4411947172 on OpenAlexaffvenue
Fartoon M. Siad, Shital Gandhi

Bibliographic record

VenueCanadian Journal of General Internal Medicine · 2025
Typearticle
Languageen
FieldMedicine
TopicAssisted Reproductive Technology and Twin Pregnancy
Canadian institutionsSinai Health SystemUniversity of Toronto
Fundersnot available
KeywordsMedicineObstetricsPregnancyIntensive care medicine

Abstract

fetched live from OpenAlex

Physiologic changes occur during pregnancy to support the growth and development of the fetus. The placental hormones lead to symptomatic and biochemical adaptations in the antepartum and postpartum periods. There are anticipated changes to virtually every maternal system with most returning to the pre-pregnancy state in the postpartum period in due course. Pregnancy is often known as nature's stress test as the lack of predictable maternal adaption may indicate an underlying previously unrecognized medical condition. This article provides a systematic overview of the key physiologic changes in a healthy pregnancy and provides the foundation for physicians caring for pregnant individuals to distinguish normal physiology from pathology.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.371
Threshold uncertainty score0.346

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.047
GPT teacher head0.328
Teacher spread0.281 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes2
Has abstractyes

Explore more

Same venueCanadian Journal of General Internal MedicineSame topicAssisted Reproductive Technology and Twin PregnancyFrench-language works237,207