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Record W4412036879 · doi:10.1002/admi.202500315

Rationalizing the Unexpected Inefficiencies of 3D Porphyrin‐MOFs as Singlet Oxygen Photosensitizers Against <i>Botrytis cinerea</i>

2025· article· en· W4412036879 on OpenAlexafffund
Océane Boudreau, Paul Asselin, Seyed Mehrzad Sajjadinezhad, Paul‐Ludovic Karsenti, Peter Moffett, Kamal Bouarab, Pierre D. Harvey

Bibliographic record

VenueAdvanced Materials Interfaces · 2025
Typearticle
Languageen
FieldChemistry
TopicMetal-Organic Frameworks: Synthesis and Applications
Canadian institutionsUniversité de Sherbrooke
FundersFonds de recherche du Québec – Nature et technologiesNatural Sciences and Engineering Research Council of CanadaHydro-QuébecUniversité de Sherbrooke
KeywordsSinglet oxygenBotrytis cinereaPorphyrinMaterials sciencePhotochemistryPhotodynamic therapyOxygenNanotechnologyBotanyChemistryOrganic chemistryBiology

Abstract

fetched live from OpenAlex

Abstract Porphyrin‐based MOFs (PMOFs) are known to be efficient photocatalysts and singlet oxygen ( 1 O 2 ) photosensitizers (PS) in solution, but their application in agriculture and food protection is practically unknown. In vitro tests on Botrytis cinerea using the renowned PCN‐222 and PCN‐224 reveal modest photo‐antifungal activities at the solid–gas interface when compared to their standalone tetrakis(4‐carboxyphenyl)porphyrin (TCPP) linker. This in‐depth study examines the direct detection of 1 O 2 (g) phosphorescence at the solid–air interface, binding of the PMOFs with the spores of B. cinerea by fluorescence microscopy, fluorescence quenching of the PMOFs by oxygen, and rates of exciton migration evaluated through the singlet‐singlet annihilation process. The conclusion is that a significant proportion of 1 O 2 is unable to escape the porous materials before deactivation, or does so too late to then be able to reach, and that excitation migration is not efficient enough to generate significant amounts of 1 O 2 directly at the MOF surface. Given that TCPP is its own interface with the gas phase, it is not hindered by these factors, which explains its higher efficiency under these circumstances.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.012
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.249
Teacher spread0.240 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

Explore more

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