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Record W4412048217 · doi:10.6026/973206300211719

Clinical and cost-effectiveness of synbiotics versus antibiotics and analgesics in post-tooth extraction socket healing: A randomized controlled trial

2025· article· en· W4412048217 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueBioinformation · 2025
Typearticle
Languageen
FieldMedicine
TopicLaser Applications in Dentistry and Medicine
Canadian institutionsTrinity Western UniversityHumber PolytechnicWestern University
Fundersnot available
KeywordsSynbioticsMedicineRandomized controlled trialDry socketDentistryWound healingClinical trialSurgeryInternal medicineMolarProbiotic

Abstract

fetched live from OpenAlex

There has been a noticeable increase in the use of alternative strategies such as herbal medicines and laser therapies to tackle a range of health issues, including oral diseases. Therefore, it is of interest to examine how synbiotics affect tooth extraction socket healing and problems. Hence, a total of 210 patients, were split into three groups of 70 individuals each. The primary outcome measures were assessed on the 3rd, 5th, and 7th days after the extraction. Group 3 patients had the highest incidence of bleeding, while group 1 had the lowest. Group 3 experienced the highest level of discomfort and swelling, while group 1 reported the lowest. Thus, post-extraction wound healing using synbiotics' benefits.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.019
Threshold uncertainty score0.324

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.030
GPT teacher head0.397
Teacher spread0.367 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it