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Record W4412074722 · doi:10.1097/qad.0000000000004289

On the compounding manifestations of racism shaping the US HIV/AIDS epidemic: why ending the HIV epidemic must address these factors for success

2025· article· en· W4412074722 on OpenAlexaff
Xiao Zang, Yi Sui, Sam Bessey, Hansel Tookes, Brandon D. L. Marshall, Bohdan Nosyk

Bibliographic record

VenueAIDS · 2025
Typearticle
Languageen
FieldMedicine
TopicHIV/AIDS Research and Interventions
Canadian institutionsSimon Fraser UniversityCentre for Advancing Health Outcomes
FundersNational Institute on Drug Abuse
KeywordsDemographyEthnic groupMen who have sex with menHealth equityMedicineIncidence (geometry)GerontologyPublic healthHuman immunodeficiency virus (HIV)VirologySociology

Abstract

fetched live from OpenAlex

OBJECTIVE: Growing racial/ethnic inequities in healthcare access and racially segregated sexual mixing contribute to persistent disparities in HIV incidence in the US. We aim to examine the extent to which eliminating racial/ethnic inequities in healthcare access could reduce disparities in HIV incidence and its interaction with assortative sexual mixing. DESIGN: A mathematical model. METHODS: We used two independently developed HIV transmission models to estimate HIV incidence among Black, Hispanic/Latino, and White/Other MSM and the corresponding incidence rate ratios (IRRs) comparing Black and Hispanic/Latino to White/Other as a measure of disparity in the four "Ending the HIV Epidemic (EHE)" counties in Georgia. We compared three scenarios: status quo; equal service access across racial/ethnic groups with reported assortative sexual mixing by race/ethnicity; and equal service access with random sexual mixing. We standardized both models to enhance comparability. RESULTS: Under the status quo, both models projected a reduction in overall HIV incidence but persistent racial/ethnic disparities, with an IRR as large as 8.3 between Black and White/Other MSM. Compared to the status quo, providing equal health service access resulted in a modest reduction in IRRs with reported assortative sexual mixing in 2030, but yielded a much greater reduction when sexual mixing was at random: IRR reduced by up to 38.8% and 58.3% between Black and White/Other MSM in the two models. CONCLUSION: This study highlights racially segregated sexual mixing as a barrier to efforts to mitigate racial/ethnic disparities in HIV incidence. Reaching EHE targets will require not only equitable healthcare access but also strategies addressing sexual racism and other structural barriers.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.007
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.410
Threshold uncertainty score0.845

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.007
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0000.001
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.089
GPT teacher head0.390
Teacher spread0.301 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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