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Pet treats, Salmonella, and antimicrobial resistance; a One Health problem

2025· article· en· W4412085016 on OpenAlexaboutno aff
Elizabeth M. Parker, Cong Li, Gregory A. Ballash, Thomas E. Wittum

Bibliographic record

VenuePreventive Veterinary Medicine · 2025
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicSalmonella and Campylobacter epidemiology
Canadian institutionsnot available
FundersNational Center for Emerging and Zoonotic Infectious DiseasesU.S. Food and Drug AdministrationCenter for Veterinary Medicine
KeywordsSalmonellaAntibiotic resistanceAntimicrobialMicrobiologyBiologyAntibioticsGeneticsBacteria

Abstract

fetched live from OpenAlex

Zoonotic pathogens, including Salmonella and antimicrobial resistant bacteria, may contaminate the food or treats consumed by our pets. These may directly impact the health of the pets or may be transferred to humans who are in close contact. To better understand the potential risk, we purchased 505 pet treats from pet and farm supply stores, grocery stores, and online retailers in the U.S. over a period of 16 months to identify and characterize Salmonella and Enterobacterales resistant to Highest Priority Critically Important Antimicrobials. We used selective media to detect Salmonella and bacteria resistant to colistin, carbapenems, fluoroquinolones, and 3 rd and 4 th generation cephalosporins. Four pig ear treats from Brazil were positive for Salmonella, with serotypes , Muenchen , Derby , Agona and Regent. We found that S. Muenchen and S. Derby were closely related to clinical and environmental isolates from the U.S., Canada, Venezuela, and Colombia. We detected three colistin resistant isolates, Klebsiella pneumoniae , Escherichia coli , and Enterobacter hormaechei , all from pig ear treats from Brazil, harboring the mcr 1.18 resistance gene on identical IncX4 plasmids. In addition, we recovered one carbapenem resistant E. coli harboring both bla KPC-2 and bla NDM-5 from a “bully stick”. We found that treats originating from North America and treats purchased in grocery stores had a lower risk of contamination with bacteria resistant to the antimicrobials tested. Outreach and extension activities are needed to increase awareness of the risks of contaminated pet treats and to highlight the importance of hand hygiene when feeding and interacting with pets.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.835
Threshold uncertainty score0.329

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.039
GPT teacher head0.297
Teacher spread0.258 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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