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Record W4412102670 · doi:10.1038/s41559-025-02751-2

Haploblocks contribute to parallel climate adaptation following global invasion of a cosmopolitan plant

2025· article· en· W4412102670 on OpenAlexafffund
Paul Battlay, Brandon T Hendrickson, Jonas I Mendez-Reneau, James S. Santangelo, Lucas J. Albano, Jonathan Wilson, Aude E. Caizergues, Nevada King, Adriana Puentes, Amelia Tudoran, Cyrille Violle, François Vasseur, Michael Foster, Caitlyn Stamps, Simon G. Innes, Rémi Allio, Fábio Angeoletto, Daniel N. Anstett, Julia Anstett, Anna Bucharová, Mattheau S. Comerford, Santiago David, Mohsen Falahati‐Anbaran, William Godsoe, César González‐Lagos, Pedro E. Gundel, Glen R. Hood, Christian Lampei, Carlos Lara, Adrián Lázaro‐Lobo, Deleon Silva Leandro, Thomas Merritt, Nora Mitchell, Mitra Mohammadi Bazargani, Angela T. Moles, Maureen Murúa, Juraj Paule, Vera Pfeiffer, Joost A. M. Raeymaekers, Diana J. Rennison, Rodrigo S. Ríos, Jennifer K. Rowntree, Adam C. Schneider, Kaitlin Stack Whitney, Ítalo Tamburrino, Acer VanWallendael, Paul Kim, Rob W. Ness, Marc T. J. Johnson, Kathryn A. Hodgins, Nicholas J. Kooyers

Bibliographic record

VenueNature Ecology & Evolution · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic diversity and population structure
Canadian institutionsUniversity of British ColumbiaLaurentian UniversityUniversity of Toronto
FundersGovernment of Canada
KeywordsBiologyLocal adaptationAdaptation (eye)Evolutionary biologyRange (aeronautics)Genetic diversityPopulationPopulation bottleneckGenetic variationColonizationEcologyAlleleGeneticsMicrosatelliteGene

Abstract

fetched live from OpenAlex

The role of rapid adaptation during species invasions has historically been minimized with the assumption that introductions consist of few colonists and limited genetic diversity. While overwhelming evidence suggests that rapid adaptation is more prevalent than originally assumed, the demographic and adaptive processes underlying successful invasions remain unresolved. Here we leverage a large whole-genome sequence dataset to investigate the relative roles of colonization history and adaptation during the worldwide invasion of the forage crop, Trifolium repens (Fabaceae). We show that introduced populations encompass high levels of genetic variation with little evidence of bottlenecks. Independent colonization histories on different continents are evident from genome-wide population structure. Five haploblocks-large haplotypes with limited recombination-on three chromosomes exist as standing genetic variation within the native and introduced ranges and exhibit strong signatures of parallel climate-associated adaptation across continents. Field experiments in the native and introduced ranges demonstrate that three of the haploblocks strongly affect fitness and exhibit patterns of selection consistent with local adaptation across each range. Our results provide strong evidence that large-effect structural variants contribute substantially to rapid and parallel adaptation of an introduced species throughout the world.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.133
Threshold uncertainty score0.497

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.249
Teacher spread0.243 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations10
Published2025
Admission routes2
Has abstractyes

Explore more

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