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Record W4412136528 · doi:10.1080/21642850.2025.2525181

Predictors of adherence to insulin therapy in type 2 diabetes mellitus: an application of the theory of planned behavior

2025· article· en· W4412136528 on OpenAlexaff
Mariane Karin de Moraes Oliveira, Uiara Aline de Oliveira Kaizer, Fernanda Freire Jannuzzi, Henrique Ceretta Oliveira, Neusa Maria Costa Alexandre, Maria Cecília Bueno Jayme Gallani, Thaís Moreira São‐João, Marília Estêvam Cornélio, Roberta Cunha Matheus Rodrigues

Bibliographic record

VenueHealth Psychology and Behavioral Medicine · 2025
Typearticle
Languageen
FieldMedicine
TopicMedication Adherence and Compliance
Canadian institutionsUniversité Laval
FundersUniversidade Estadual de Campinas
KeywordsInsulinInternal medicineDiabetes mellitusType 2 diabetesMedicineType 2 Diabetes MellitusTheory of planned behaviorMedication adherenceEndocrinologyComputer scienceControl (management)

Abstract

fetched live from OpenAlex

Background: Non-adherence to medication therapy in type 2 diabetes mellitus (DM2) is prevalent. Theoretical models have been used to identify the proximal determinants of behavior. Aim: To identify the direct psychosocial predictors of adherence to insulin therapy based on Theory of Planned Behavior (TPB), among outpatients with DM2. Methods: = 70), measurements of insulin adherence and A1C were again measured. Multiple linear regression, via generalized linear models and Multiple Poisson regression, with robust variance analysis were used, for quantitative and categorical outcomes, respectively. Results: One point in the Intention score led to a mean increase of 12.5% in the proportion of insulin doses, and there was a mean increase of 25% in the probability of the person taking insulin every day or practically every day. Attitude was a predictor of Intention. The moderation analysis demonstrated that higher levels of Perceived Behavioral Control weakened the effect of Attitude on Intention. Conclusions: The results showed that Intention was predictor of behavioral measure of adherence and the proportion of insulin doses. Attitude was predictor of Intention and Perceived Behavioral Control moderated the effect of Attitude and Subjective Norm on Intention. These findings highlight the importance of developing interventions that prioritize motivational strategies to enhance insulin adherence in the clinical practice. However, future studies with larger sample sizes and the inclusion of belief assessments are recommended to optimize the understanding of the psychosocial determinants of insulin adherence among outpatients with DM2.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.188
Threshold uncertainty score0.260

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.094
GPT teacher head0.452
Teacher spread0.358 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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