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Record W4412363888 · doi:10.1016/j.diabres.2025.112365

Prevalence of diabetic kidney disease by world region of birth among immigrants and long-term residents of Canada with type 2 diabetes

2025· article· en· W4412363888 on OpenAlexafffundabout
Sebat Mohamed, Lorraine L. Lipscombe, Jennifer Lipscombe, Chris Kenaszchuk MSc, Deva Thiruchelvam, Baiju R. Shah, Ghazal S. Fazli, Gillian L. Booth, Laura C. Rosella, Calvin Ke

Bibliographic record

VenueDiabetes Research and Clinical Practice · 2025
Typearticle
Languageen
FieldMedicine
TopicChronic Kidney Disease and Diabetes
Canadian institutionsSt. Michael's HospitalSunnybrook Health Science CentreInstitute for Clinical Evaluative SciencesTrillium Health CentreWomen's College HospitalUniversity Health NetworkUniversity of Toronto
FundersInstitut canadien d'information sur la santéIndustrial Research and Consultancy CentreUniversity of TorontoOntario Ministry of Health and Long-Term CareNovo NordiskInstitute for Clinical Evaluative Sciences
KeywordsMedicineDiabetes mellitusImmigrationTerm (time)Type 2 diabetesKidney diseaseDiseaseInternal medicineGerontologyPediatricsDemographyEndocrinology

Abstract

fetched live from OpenAlex

AIMS: To measure the prevalence of diabetic kidney disease (DKD) among immigrants and long-term residents with type 2 diabetes (T2D). METHODS: We conducted a population-based retrospective cohort study in Ontario, Canada among adults aged 20-79 years with T2D. The exposure was world region of birth (immigrants); long-term residents were the comparison group. The outcome was DKD, defined by the Kidney Disease: Improving Global Outcomes (KDIGO) categories. We measured the age-sex standardized prevalence of DKD and constructed logistic regression models to compute adjusted odds ratios (OR) estimating the association between the exposure and outcome. RESULTS: We included 210,693 immigrants (mean age 59.8 [standard deviation 10.8] years, 54.3 % male) and 539,632 long-term residents (mean age 64.1 [10.4] years, 56.1 % male). Immigrants born in East Asia had the highest prevalence and adjusted odds of the KDIGO low-risk category (76.6 %, OR 1.59, 1.53-1.64). Immigrants born in Southeast Asia had the lowest prevalence of the KDIGO low-risk category (64.0 %), and the highest prevalence and adjusted odds of the moderately-increased, high, and very-high risk KDIGO categories (OR: 1.21, [1.18-1.25]; 1.20, 1.14-1.26; 1.18, 1.12-1.25) compared to long-term residents. CONCLUSIONS: There is substantial variation in the prevalence of DKD among immigrants according to world region of birth.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.052
Threshold uncertainty score0.104

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0020.003
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.026
GPT teacher head0.370
Teacher spread0.344 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes3
Has abstractno

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