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Record W4412368733 · doi:10.21649/akemu.v31ispl2.5827

Ethical issues of Artificial Intelligence in Healthcare in Developing Countries: A Systematic Review of Empirical Studies

2025· review· en· W4412368733 on OpenAlexaff
Khunsa Junaid, Mehreen Nasir, Saadia Rafique, Amber Arshad, Meha Siddiqui, Muhammad Ali Junaid

Bibliographic record

VenueAnnals of King Edward Medical University · 2025
Typereview
Languageen
FieldMedicine
TopicArtificial Intelligence in Healthcare and Education
Canadian institutionsContinental (Canada)
Fundersnot available
KeywordsMedicineHealth careSystematic reviewDeveloping countryEngineering ethicsManagement scienceMEDLINEEconomic growthLawEngineering

Abstract

fetched live from OpenAlex

Significant improvements in diagnosis, treatment, and patient outcomes are possible with the use of artificial intelligence (AI) in healthcare. However, there is still a lack of research on ethical issues, especially in developing nations. This systematic review, conducted following PRISMA 2020 guidelines, identified 22 studies from a comprehensive search of 2977 records published between January 2019 and May 2024. Ethical themes were categorised using Jobin et al.'s framework and the European Commission's Ethics Guidelines for Trustworthy AI (EGTAI), while studies were evaluated using Kitchenham and Charters' quality checklist. Nine main ethical issues were identified by thematic analysis; the most often discussed issues were data privacy and justice, followed by patient safety, autonomy, and cyber-security. Benevolence received the least attention, while notable ethical conundrums included bias, fairness, discrimination, algorithmic transparency, and data protection. This systematic review highlights the need for stronger regulatory frameworks, ethical guidelines, and governance structures to ensure responsible AI integration in healthcare, particularly in developing countries, and calls for further research to address existing gaps.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.020
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.081
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0050.020
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0040.000
Bibliometrics0.0010.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.450
GPT teacher head0.575
Teacher spread0.126 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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