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Record W4412413806 · doi:10.1101/2025.07.11.25331398

Edge-tuning of artificial intelligence improves diagnostic performance for <i>Schistosomiasis haematobium</i> in a rural setting of Côte d’Ivoire

2025· preprint· en· W4412413806 on OpenAlexaff
María Díaz de León Derby, Jean T. Coulibaly, Elena Dacal, Kigbafori D. Silué, Daniel Cuadrado, David Bermejo-Peláez, Jaime García-Villena, Lin Lin, Karla Fisher, Jason R. Andrews, Daniel A. Fletcher, Miguel Luengo-Oroz, Isaac I. Bogoch

Bibliographic record

VenuemedRxiv · 2025
Typepreprint
Languageen
FieldImmunology and Microbiology
TopicParasites and Host Interactions
Canadian institutionsUniversity of TorontoToronto General HospitalUniversity Health Network
Fundersnot available
KeywordsCote d ivoireSchistosomiasisSchistosoma haematobiumEnhanced Data Rates for GSM EvolutionGeographyArtificial intelligenceComputer scienceHumanitiesBiologyHelminthsZoologyArt

Abstract

fetched live from OpenAlex

Abstract Background Schistosomiasis affects over 200 million people and causes significant urogenital and gastrointestinal morbidity. Mass drug administration (MDA) with praziquantel is used to mitigate severe illness and reduce infection rates. Portable microscopy, combined with artificial intelligence (AI), offers a novel method for schistosomiasis screening in low-resource settings. This study tested whether re-training AI models for Schistosoma egg detection with local field data, a process we call “edge-tuning”, could improve the model’s performance on the following field day. Methods This study in Côte d’Ivoire evaluated a portable microscope (NTDscope) for Schistosoma haematobium screening. Urine samples from 100 community members were analyzed using AI models on the NTDscope and traditional light microscopy. Starting AI models, trained on images from a previous version of the NTDscope, were edge-tuned after the first day of sample collection using cloud-based image annotation and re-training. Starting and edge-tuned models were evaluated at confidence thresholds optimizing for sensitivity, specificity, or egg counting. Findings For all thresholds, edge-tuned models performed better than starting AI models. Compared to manual counting of eggs on the NTDscope, sensitivity of the starting AI model on day 2 ranged from 59.3%-75.5%, with specificity ranging from 46.7%-85.7%. After edge-tuning, sensitivity increased to 77.8%-100%, with specificity from 78.6%-100%. Compared to light microscopy, edge-tuned AI models had comparable performance to manual counting from NTDscope images. Interpretation Portable microscopy is an effective solution for rapid, on-site schistosomiasis screening. AI- based egg detection increases diagnostic throughput while maintaining good performance. This study demonstrates that edge-tuning AI models with local data significantly improves their performance and can be performed in low-resource settings, making the combined technologies effective tools for monitoring schistosomiasis programs in endemic areas.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.246
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.298
Teacher spread0.277 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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