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Record W4412487046 · doi:10.62713/aic.3917

Comparison of Laparoscopic and Robotic Lateral Lymph Node Dissection for Rectal Cancer: A Systematic Review and Meta-analysis of Short- and Long-term Outcomes

2025· review· en· W4412487046 on OpenAlexaboutno aff
Fabio Rondelli, Alessio Lucarini, Giovanni Maria Garbarino, Graziano Ceccarelli, Valentina Tassi, Gioia Brachini, Edoardo Maria Muttillo, Leonardo Di Cicco, Francesco Saverio Li Causi, Alice Ceccacci, Paolo Mercantini, Gianluca Costa

Bibliographic record

VenueAnnali Italiani di Chirurgia · 2025
Typereview
Languageen
FieldMedicine
TopicColorectal Cancer Surgical Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineDissection (medical)Meta-analysisColorectal cancerLymph nodeGeneral surgeryTerm (time)CancerSurgeryInternal medicine

Abstract

fetched live from OpenAlex

AIM: The importance of lateral lymph node dissection (LLND) for advanced low rectal cancer is still questioned, but selected patients might benefit from this procedure. The purpose of this study was to compare robotic LLND (R-LLND) versus laparoscopic LLND (L-LLND) to identify the safety, feasibility, and advantages of R-LLND. METHODS: PubMed, Scopus, and Cochrane databases were searched for studies assessing the benefit of R-LLND over L-LLND. Pooled odds ratios (OR) and weighted mean difference (WMD) were obtained using models with random effects. The risk of bias was evaluated with the Newcastle-Ottawa scale. RESULTS: Six studies were included in our analysis for a total of 652 patients (316 robotic and 336 laparoscopic). The R-LLND group had a longer operative time (WMD 60.46, p = 0.02) and less blood loss (WMD –22.33, p = 0.01). Differences were found in the postoperative length of stays (7 days ± 1.2 and 14 ± 5.2 versus 7 days ± 0.3 and 16 ± 18.5, WMD –1.30, p = 0.03) and in the mean time to regular diet (3 days ± 0.5 and 5 ± 2.3 versus 3 days ± 1.2 and 6 ± 3.8, WMD –0.60 p = 0.01); a slightly higher number of harvested lateral lymph nodes was present in the L-LLND group (WMD 1.23, p = 0.02). CONCLUSIONS: Our work demonstrates a slight benefit from the robotic approach when performing LLND in terms of intra- and peri-operative outcomes, despite not reaching statistical significance a trend in favor of robotic surgery is evident in almost all the analyzed topic.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.011
metaresearch head score (Gemma)0.025
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: Meta-analysis
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.018
Threshold uncertainty score0.056

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0110.025
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0180.033
Bibliometrics0.0050.006
Science and technology studies0.0010.001
Scholarly communication0.0030.002
Open science0.0020.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.139
GPT teacher head0.452
Teacher spread0.312 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designMeta-analysis
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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