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Record W4412491906 · doi:10.1007/s12311-025-01885-0

The Natural History Study and Biomarker Collection of the Clinical Research Consortium for the Study of Cerebellar Ataxia (CRC-SCA)

2025· review· en· W4412491906 on OpenAlexaff
Yi-Cheng Lin, Nadia Amokrane, Sandie Worley, Lauren R. Moore, Andrew Rosen, Laura P. Crespo, Kelsey Trace, Tetsuo Ashizawa, Andrew Billnitzer, Susan B. Perlman, Aaron J. Fisher, Khalaf Bushara, Michael D. Geschwind, Cameron Dietiker, Christopher M. Gomez, Mahesh Padmanaban, Puneet Opal, Rizwan Akhtar, Henry L. Paulson, Sharan R. Srinivasan, Amy Ferng, Frank D. Ferrari, Chiadi U. Onyike, Ann Fishman, Sarah H. Ying, Ashley Paul, Jeremy D. Schmahmann, Christopher D. Stephen, Anoopum S. Gupta, Chih-Chun Lin, S. H. Subramony, Matthew R. Burns, George Wilmot, Antoine Duquette, Theresa Zesiewicz, Marie Y. Davis, Ali G. Hamedani, Joaquín A. Vizcarra, Stefan M. Pulst, Sharon Primeaux, Gülin Öz, Vikram G. Shakkottai, Liana S. Rosenthal, Sheng‐Han Kuo

Bibliographic record

VenueThe Cerebellum · 2025
Typereview
Languageen
FieldNeuroscience
TopicGenetic Neurodegenerative Diseases
Canadian institutionsCentre Hospitalier de l’Université de Montréal
FundersNational Institute of Neurological Disorders and StrokeNational Institutes of HealthNational Ataxia Foundation
KeywordsSpinocerebellar ataxiaBiomarkerNatural history studyAtaxiaMedicineNeuroscienceNatural historyNeuroimagingNeurologyCerebellar ataxiaDiseasePsychologyOncologyPathologyInternal medicineBiologyGenetics

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.006
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesScience and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.726
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0050.006
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.001
Science and technology studies0.0020.002
Scholarly communication0.0000.000
Open science0.0030.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.256
GPT teacher head0.448
Teacher spread0.192 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractno

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