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Record W4412512602 · doi:10.26434/chemrxiv-2025-vj4fk

How the Discreteness of the Periodic Table Undermines Machine Learning Predictions

2025· preprint· en· W4412512602 on OpenAlexafffund
Zhibo Wang, Alexander Davis, Rajarshi Dutta, Ihor Neporozhnii, Oleksandr Voznyy

Bibliographic record

VenueChemRxiv · 2025
Typepreprint
Languageen
FieldChemistry
TopicAnalytical Chemistry and Chromatography
Canadian institutionsUniversity of Toronto
FundersNatural Sciences and Engineering Research Council of CanadaUniversity of TorontoGovernment of OntarioCompute Canada
KeywordsTable (database)Computer scienceArtificial intelligencePeriodic tableMachine learningStatistical physicsCognitive sciencePsychologyPhysicsData miningQuantum mechanics

Abstract

fetched live from OpenAlex

The discovery of novel optoelectronic materials relies on accurate bandgap characterization, enabling efficient exploration of uncharted materials space. Machine learning (ML) is a promising approach to accelerate materials discovery, yet accurate bandgap prediction remains a persistent challenge. This study finds that poor ML performance is not solely attributable to insufficient data or model robustness but rather to the intrinsic complexity and discontinuous nature of chemical space. The lack of a continuous trend in the periodic table fundamentally limits ML models, preventing them from leveraging systematic patterns. While smooth trends exist for properties like total and formation energies, bandgaps exhibit inherent fragmentation, leading models to memorize localized correlations rather than learn universal physical laws. Consequently, increasing dataset size fails to improve predictions. Thus, the core challenge of bandgap prediction lies not in model scale or complexity, but in bridging the discretized foundations of the periodic table itself.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.029
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.022

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.029
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.002
Scholarly communication0.0040.005
Open science0.0020.002
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.227
Teacher spread0.212 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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