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Record W4412527389 · doi:10.1002/sim.70194

A Simple Diagnostic for the Positivity Assumption for Continuous Exposures

2025· article· en· W4412527389 on OpenAlexafffund
Erica E. M. Moodie, Juliana Schulz

Bibliographic record

VenueStatistics in Medicine · 2025
Typearticle
Languageen
FieldMathematics
TopicAdvanced Causal Inference Techniques
Canadian institutionsHEC MontréalMcGill University
FundersFonds de Recherche du Québec - SantéNatural Sciences and Engineering Research Council of CanadaCanadian Institutes of Health Research
KeywordsSimple (philosophy)StatisticsComputer scienceEconometricsMathematics

Abstract

fetched live from OpenAlex

The positivity or experimental treatment assignment assumption is a fundamental requirement in causal analyses, invoked to ensure that identifiability holds without extrapolating beyond what the observed data can reveal. Positivity is well understood in the context of binary and categorical treatments, and has been thoroughly discussed-from how the assumption can be assessed to approaches that may be used when the assumption is suspected not to hold. Positivity extends to the context of continuous exposures, such as doses, however it has been given very little formal consideration. In this manuscript, we propose a method for assessing whether the positivity assumption is violated in a given dataset, relying on a principled concept in regression analysis. We demonstrate the diagnostic tool in various simulated settings, as well as in an application involving warfarin dosing.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.056
metaresearch head score (Gemma)0.407
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.056
Threshold uncertainty score0.294

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0560.407
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0040.003
Science and technology studies0.0020.008
Scholarly communication0.0040.008
Open science0.0040.005
Research integrity0.0070.008
Insufficient payload (model declined to judge)0.0160.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.085
GPT teacher head0.464
Teacher spread0.379 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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