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Record W4412565103 · doi:10.1016/j.jhin.2025.07.002

The Omicron variant significantly increases viral load emissions in healthcare settings: implication for healthcare workers

2025· article· en· W4412565103 on OpenAlexafffund
Florent Rossi, Karyne Pelletier, Marc Veillette, Bianka Paquet-Bolduc, Caroline Duchaine

Bibliographic record

VenueJournal of Hospital Infection · 2025
Typearticle
Languageen
FieldMedicine
TopicInfection Control and Ventilation
Canadian institutionsInstitut universitaire de cardiologie et de pneumologie de Québec
FundersFonds de recherche du QuébecInstitut de Recherche Robert-Sauvé en Santé et en Sécurité du Travail
KeywordsMedicineHealth careHealthcare workerHealthcare systemViral loadVirologyEnvironmental healthHuman immunodeficiency virus (HIV)

Abstract

fetched live from OpenAlex

BACKGROUND: The SARS-CoV-2 Omicron variant is transmitted via contaminated droplets and aerosols, raising concerns in healthcare settings where poor ventilation and high patient density can increase airborne viral load. AIM: This study aimed to assess real-world exposure of healthcare workers to COVID-19-positive patients isolated in designated hospital areas, using continuous 24-h air sampling. METHODS: Air sampling was conducted inside 10 hospital rooms hosting a succession of 38 patients who tested positive for SARS-CoV-2. Sampling was performed using 37-mm cassettes placed near the patients' heads. The Omicron variant in the air was detected by RT-qPCR, with results expressed as emission rates based on air changes per hour for each room and correlated with the onset of patients' symptoms. FINDINGS: genomes/h per patient. Expectoration was the sole symptom significantly affecting emission rates, with patient suffering from it exhibiting values three times higher than patients without. Additionally, the room accounted for half of the variance in emission rates, suggesting that the number of patients and the room's prior usage are key determinants of viral particle exposure. CONCLUSION: Our findings indicate that healthcare workers face significant exposure when providing care in rooms with positive patients, even when mechanically ventilated. Greater attention should be given to treating and managing these spaces to reduce the potential for viral transmission toward healthcare workers.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.094
Threshold uncertainty score0.342

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.309
Teacher spread0.300 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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