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Record W4412595724 · doi:10.1097/ico.0000000000003936

Eye Donation From Individuals Receiving Medical Assistance in Dying: Retrospective Chart Review of the Eye Bank of Canada (Ontario Division)

2025· article· en· W4412595724 on OpenAlexaffabout
Irina Sverdlichenko, Christine Humphreys, Brendan G. Ko, Mor Bareket, Clara C. Chan

Bibliographic record

VenueCornea · 2025
Typearticle
Languageen
FieldMedicine
TopicOrgan Donation and Transplantation
Canadian institutionsBank of CanadaUniversity of Toronto
Fundersnot available
KeywordsMedicineDonationReferralTissue DonationDemographicsFamily medicineEye bankMedical recordTransplantationRetrospective cohort studyOrgan donationHealth careOphthalmologySurgeryDemographyCornea

Abstract

fetched live from OpenAlex

PURPOSE: In Canada, Medical Assistance in Dying (MAiD) became a legal option for patients in 2016. The characteristics of MAiD donors, specifically for ocular tissue transplantation, have not been studied. The goal of this study was to explore the demographics and health status of these individuals. METHODS: A retrospective chart review of MAiD donors from the Eye Bank of Canada (Ontario Division) from January 2019 to March 2024 was conducted. Variables recorded included demographics, medical status, mechanism of death, consent and referral process, and tissue utilization. RESULTS: There were 475 eye donors (6.1% of all eye donors) who underwent the MAiD provision. The average age of donors was 70 years (SD: 5.42), and 50.5% (240/475) were male. Cancer was the most common mechanism of death, in 70% (332) of cases. First-person consent was obtained only 35% (164/474) of the time for ocular tissue donation, and 90% of donors (428/475) were referred from hospitals. Sixty-three percent of eyes were eligible for transplantation, while 37% were eligible for research and training. The most common surgical indication for transplant was endothelial dystrophies/failure (35%, 167/484). CONCLUSIONS: This study highlights the unique characteristics of eye donors who chose the MAiD provision. Hospitals made up 90% of MAiD referrals, and only 35% of MAiD donors consented on their own behalf. Efforts should be made to expand referrals for MAiD donation from nonhospital organizations. Furthermore, once MAiD eligibility has been determined, support should be provided to health care providers to navigate difficult discussions around donation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.548
Threshold uncertainty score0.895

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.261
Teacher spread0.252 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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