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A hierarchical network model for the estimate of the energy expenditure in individuals with type 1 diabetes

2025· article· en· W4412603708 on OpenAlexaff
Eleonora M. Aiello, Chiara Toffanin, Michael C. Riddell, Corby K. Martin, Susana R. Patton, Robin L. Gal, Francis J. Doyle

Bibliographic record

VenueEngineering Applications of Artificial Intelligence · 2025
Typearticle
Languageen
FieldMedicine
TopicDiabetes Management and Research
Canadian institutionsYork University
FundersNational Institute of General Medical SciencesLeona M. and Harry B. Helmsley Charitable TrustMinistero dell’Istruzione, dell’Università e della RicercaEuropean CommissionNutrition Obesity Research Center, University of North CarolinaLouisiana Clinical and Translational Science CenterNational Institute of Diabetes and Digestive and Kidney DiseasesDexcom
KeywordsComputer scienceType 2 diabetesType (biology)Energy expenditureDiabetes mellitusMedicineInternal medicineEndocrinology

Abstract

fetched live from OpenAlex

Total daily energy expenditure (TDEE) is impacted by many medical conditions, such as diabetes. In the case of type 1 diabetes (T1D), individuals need to have an accurate assessment of the energy expenditure in real-time to avoid dietary imbalance, and improve glycemic control. This work proposes a hierarchical Long Short-Term Memory (LSTM)-based modeling approach to predict real-time continuous energy expenditure, expressed as metabolic equivalents (METs), for individuals with T1D on a 24-hour basis by leveraging the step count and heart rate data from a wrist-band smartwatch. To deal with the inter- and intra-individual variability, the proposed model uses three different LSTMs to capture population, activity-type and subject scale information. To evaluate the impact of the components of the hierarchy, the performance of the proposed hierarchical model was assessed at each level. The results show that the combination of population data, such as heart rate and step counts, with individual data in a hierarchical architecture helps to achieve superior prediction performance, than using only individual heart rate and step counts data.Additionally, compared to non-hierarchical modeling, the hierarchical modeling can provide precise and individualized prediction of the METs categories, as it allows the integration of the variation at different levels of the hierarchy. This model can be used to augment current automated insulin delivery (AID) systems to adapt insulin infusion according to the predicted activity intensity and compensate for glycemic perturbations due to exercise.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.967
Threshold uncertainty score0.161

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.303
Teacher spread0.283 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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