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Record W4412607413 · doi:10.1200/cci-24-00317

Extraction of Social Determinants of Health From Electronic Health Records Using Natural Language Processing

2025· article· en· W4412607413 on OpenAlexaff
Z Chen, Patricia Lasserre, Angela Lin, Rasika Rajapakshe

Bibliographic record

VenueJCO Clinical Cancer Informatics · 2025
Typearticle
Languageen
FieldHealth Professions
TopicFood Security and Health in Diverse Populations
Canadian institutionsUniversity of British ColumbiaUniversity of British Columbia, Okanagan CampusKelowna General Hospital
Fundersnot available
KeywordsPipeline (software)Benchmark (surveying)Artificial intelligenceComputer scienceSocial determinants of healthNatural language processingMachine learningSocial mediaMedicinePublic healthWorld Wide WebNursingGeography

Abstract

fetched live from OpenAlex

PURPOSE: Social Determinants of Health (SDoH) have a significant effect on health outcomes and inequalities. SDoH can be extracted from electronic health records (EHR) to aid policy development and research to improve population health. Automated extraction using artificial intelligence (AI) can improve efficiency and cost-effectiveness. The focus of this study was to autonomously extract comprehensive SDoH details from EHR using a natural language processing (NLP)-based AI pipeline. MATERIALS AND METHODS: A curated set of 1,000 BC Cancer clinical documents with concentrated SDoH information served as the reference standard for training and evaluating NLP models. Two pipelines were used: an open-source pipeline trained on the annotated medical documents and an industrial pretrained solution used as a benchmark. Three experiments optimized the first pipeline's performance, assessing the effect of including subtype word positions during training. The superior open-source pipeline was then used to extract SDoH information from 13,258 oncology documents. RESULTS: The open-source pipeline achieved an average F1 score accuracy of 0.88 on the validation data set for extracting 13 SDoH factors, surpassing the benchmark by 5%. It excelled in detailed subtype extraction, while the benchmark performed better in identifying rarely annotated SDoH information in BC Cancer data set. Overall, 60,717 SDoH factors and associated details were extracted from BC Cancer EHR oncology documents. The most frequently extracted SDoH factors included tobacco use, employment status, marital status, alcohol consumption, and living status, occurring between 8k to 12k times. CONCLUSION: This study demonstrates the potential of an NLP pipeline to extract SDoH factors from clinical notes, with strong performance on limited data, although data set-specific adjustments are needed for broader application across institutions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.017
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.013
Threshold uncertainty score0.026

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.017
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0070.005
Science and technology studies0.0010.001
Scholarly communication0.0020.002
Open science0.0010.002
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.272
GPT teacher head0.624
Teacher spread0.351 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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