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Record W4412613719 · doi:10.1093/pch/pxaf013

Managing newborns at risk for neonatal abstinence syndrome (NAS)/neonatal opioid withdrawal syndrome (NOWS): Updates and emerging best practices

2025· article· en· W4412613719 on OpenAlexaff
Michael Narvey, Danica Hamilton, Vanessa Paquette

Bibliographic record

VenuePaediatrics & Child Health · 2025
Typearticle
Languageen
FieldMedicine
TopicPrenatal Substance Exposure Effects
Canadian institutionsCanadian Paediatric Society
Fundersnot available
KeywordsMedicineOpioidAbstinenceWithdrawal syndromeIntensive care medicinePediatricsAnesthesiaPsychiatryInternal medicine

Abstract

fetched live from OpenAlex

The incidence of newborns at risk for withdrawal due to antenatal substance exposure has increased rapidly, presenting significant health and early developmental concerns. Access to culturally safer, trauma-informed prenatal care and support for opioid consumption improves health outcomes for both the mother/birthing parent and the fetus. Newborns are at high risk for experiencing symptoms of abstinence or withdrawal that require assessment and non-pharmacological support in the early neonatal period and may go on to require pharmacological treatment. This position statement focuses specifically on women/persons with a substance-exposed pregnancy (SEP) who are taking opioids, their newborns, and the effects of withdrawal and management strategies on newborns. This statement is inclusive of all families, as defined and determined for themselves and representing many structures and identities. Health care team communication, language, and terminology must be culturally safer, trauma-informed, and individualized to meet each family's needs and expressed identity.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.017
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.006
Threshold uncertainty score0.024

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0050.017
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0010.001
Scholarly communication0.0020.003
Open science0.0020.002
Research integrity0.0020.005
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.284
Teacher spread0.275 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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