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Record W4412626098 · doi:10.1093/scan/nsaf076

Mapping neural signatures of face processing in young children: an OPM-MEG study

2025· article· en· W4412626098 on OpenAlexafffund
Kristina Safar, Marlee M. Vandewouw, Natalie Rhodes, Julie Sato, Margot J. Taylor

Bibliographic record

VenueSocial Cognitive and Affective Neuroscience · 2025
Typearticle
Languageen
FieldNeuroscience
TopicFunctional Brain Connectivity Studies
Canadian institutionsHolland Bloorview Kids Rehabilitation HospitalUniversity of TorontoHospital for Sick Children
FundersCanadian Institutes of Health ResearchSimons Foundation Autism Research Initiative
KeywordsMagnetoencephalographyPsychologyNeuroimagingInsulaAutism spectrum disorderAutismFunctional magnetic resonance imagingFusiform face areaFace perceptionNeuroscienceCognitive psychologyDevelopmental psychologyElectroencephalographyPerception

Abstract

fetched live from OpenAlex

Facial expressions are fundamental to social communication, with emotional face processing developing throughout childhood. However, the neural mechanisms underlying this process in young children remain underexplored due to challenges in neuroimaging this population. Optically pumped magnetometers (OPMs), a wearable magnetoencephalography (MEG) technology, offer potential advantages for studying these responses early in life. This study investigated evoked responses and functional connectivity in 45 children (3-5 years) during an emotional face processing task using OPM-MEG. The M170 component, a key marker of face processing, and whole-brain functional connectivity of eight regions of interest were assessed. Children exhibited a robust M170 response to emotional faces in the bilateral fusiform gyri. Peak amplitude increased with age, but no significant latency changes were observed. A significant network of increased connectivity following emotional face onset, involving connections between the amygdalae, insulae, occipital, and frontal regions was found. This study provides the first evidence of M170 responses and large-scale connectivity to emotional faces in young children using OPM-MEG. Findings highlight the feasibility of OPMs for developmental neuroimaging and provide insights into the maturation of emotion-related neural circuits in early childhood. These results establish a foundation for future face processing research in clinical paediatric populations, such as autism.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.006
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.449
Threshold uncertainty score0.879

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.006
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.002
Science and technology studies0.0010.001
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.318
Teacher spread0.287 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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