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Record W4412641595 · doi:10.1183/13993003.00949-2025

Reply to: Type 2 inflammatory biomarkers in asthma and COPD: what we think we know

2025· letter· en· W4412641595 on OpenAlexafffund
C.A. Celis-Preciado, Samuel Lemaire‐Paquette, Philippe Lachapelle, Simon Couillard

Bibliographic record

VenueEuropean Respiratory Journal · 2025
Typeletter
Languageen
FieldMedicine
TopicAsthma and respiratory diseases
Canadian institutionsCentre Hospitalier Universitaire de SherbrookeUniversité de Sherbrooke
FundersFonds de Recherche du Québec - SantéUniversité de SherbrookeCanadian Allergy, Asthma and Immunology Foundation
KeywordsMedicineCOPDAsthmaIntensive care medicineImmunologyInternal medicine

Abstract

fetched live from OpenAlex

Extract We thank L. Menon and co-workers for their insightful comments on our article “Phenotyping the responses to systemic corticosteroids in the management of asthma attacks (PRISMA)” [1]. They raise pertinent points regarding the practicality of biomarker testing during asthma exacerbations, the potential sufficiency of blood eosinophil count (BEC) alone to guide corticosteroid therapy, and the observation of sex-related differences in type 2 inflammatory biomarker profiles.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.028
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.040
Threshold uncertainty score0.028

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.028
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0010.001
Science and technology studies0.0030.002
Scholarly communication0.0030.005
Open science0.0020.001
Research integrity0.0400.034
Insufficient payload (model declined to judge)0.0080.010

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.267
Teacher spread0.250 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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