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Record W4412687219 · doi:10.1186/s12893-025-03056-8

Prevalence and surgical outcomes of pediatric intussusception in ethiopia: a systematic review and meta-analysis

2025· review· en· W4412687219 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueBMC Surgery · 2025
Typereview
Languageen
FieldMedicine
TopicGastrointestinal disorders and treatments
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineIntussusception (medical disorder)Meta-analysisSurgeryGeneral surgeryMEDLINE

Abstract

fetched live from OpenAlex

BACKGROUND: Intussusception is the leading cause of pediatric abdominal emergencies worldwide, requiring timely diagnosis and intervention to prevent life-threatening complications. In low-resource settings such as Ethiopia, delayed presentation and limited access to non-surgical management often necessitate surgical intervention. However, comprehensive data on surgical outcomes and complications remain scarce. The aim of this study is to evaluate the epidemiology, clinical presentation, surgical management, and postoperative outcomes of pediatric intussusception in Ethiopia. METHODS: A systematic review was conducted following PRISMA guidelines. Relevant studies were retrieved from PubMed, Scopus, Web of Science, and Google Scholar. Data were extracted on patient demographics, clinical presentation, diagnostic. methods, surgical procedures, complications, and mortality. Quality assessment was performed using the Newcastle-Ottawa Scale. Meta-analysis was conducted using a random-effects model with heterogeneity assessed by I² statistics. Publication bias was evaluated using Egger's test. RESULTS: Seven studies with a total of 672 patients were included. The mean age of affected children was 12 months (95% CI: 11.35, 12.67), with a male predominance (66%). Delayed presentation was common, with a mean time of 3.1 days from symptom onset. The classic triad of symptoms-abdominal pain, bloody stools, and a palpable mass-was present in 52% of cases (I² = 96.24%). Ultrasound was the most common diagnostic tool (74%). The most frequent surgical intervention was manual reduction (62%), followed by bowel resection with anastomosis (35%) and stoma creation. The overall complication rate was 26%, with surgical site infections (15%) being the most common. The pooled mortality rate was 9% (95% CI: 5%, 13%), significantly higher than in high-income countries. Egger's test (p = 0.03) suggested potential publication bias. CONCLUSION: This study found that surgically managed pediatric intussusception in Ethiopia had a high morbidity and mortality rate. These outcomes may reflect delays in presentation, and advanced disease at intervention. The development and implementation of context-specific clinical guidelines could help optimize care and improve survival rates. In addition, further research is needed to evaluate the impact of non-surgical reduction techniques.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.894
Threshold uncertainty score0.872

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0110.002
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.107
GPT teacher head0.374
Teacher spread0.267 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it