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Record W4412709190 · doi:10.1186/s12871-025-03270-0

Chordae tendineae rupture: a rare cause of tricuspid regurgitation following coronary artery bypass grafting

2025· article· en· W4412709190 on OpenAlexaff
Dana Wu, Jian Ye, Julena Foglia

Bibliographic record

VenueBMC Anesthesiology · 2025
Typearticle
Languageen
FieldMedicine
TopicCardiac Valve Diseases and Treatments
Canadian institutionsVancouver General HospitalUniversity of British Columbia
Fundersnot available
KeywordsMedicineCardiopulmonary bypassCardiologyTricuspid valveInternal medicineRegurgitation (circulation)ArterySurgery

Abstract

fetched live from OpenAlex

BACKGROUND: Tricuspid regurgitation is classified broadly by its etiology being either structural or functional. New or worsening tricuspid regurgitation upon weaning from cardiopulmonary bypass is rare and often functional. However, iatrogenic structural causes are possible and should be investigated with a high index of suspicion when issues separating from cardiopulmonary bypass arise. Currently, isolated coronary artery bypass grafting is not a class I indication for intraoperative transesophageal echocardiography, leading to significant practice variation. However, intraoperative transesophageal echocardiography, even during routine isolated coronary artery bypass grafting, can be a valuable tool in differentiating between functional and structural causes of post-cardiopulmonary bypass tricuspid regurgitation, allowing for prompt surgical intervention when required. CASE PRESENTATION: We report a case of a 63-year-old female, American Society of Anesthesiologists physical status 4, who underwent an isolated coronary artery bypass grafting surgery and subsequently developed difficulty weaning from cardiopulmonary bypass after completion of revascularization. Intraoperative transesophageal echocardiography revealed severe tricuspid regurgitation with evidence of right ventricular dysfunction which was initially presumed to be functional in etiology. However, further investigation with transesophageal echocardiography revealed a flail posterior tricuspid valve leaflet with an anteriorly directed jet. The decision was made to re-institute cardiopulmonary bypass for prompt surgical correction of what was determined to be an acutely ruptured chordae tendineae originating from an anomalous papillary muscle of the posterior tricuspid leaflet. Successful surgical repair was performed with neochord implantation and a 26 mm tricuspid annuloplasty ring. Final intraoperative transesophageal echocardiography demonstrated mild residual tricuspid regurgitation with normal biventricular size and systolic function and the patient was subsequently weaned off cardiopulmonary bypass without issue. CONCLUSIONS: We describe a case of a ruptured chordae tendineae causing new severe tricuspid regurgitation after an isolated coronary bypass grafting surgery. The use of intraoperative transesophageal echocardiography was essential for the prompt diagnosis and surgical correction of this rare structural cause of post-cardiopulmonary tricuspid regurgitation. This case lends support to the routine use of intraoperative transesophageal echocardiography in isolated coronary artery bypass grafting surgery.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.582

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.326
Teacher spread0.308 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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