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Record W4412727769 · doi:10.1111/petr.70148

A Novel Combined Surgical and Interventional Radiology Vascular Reconstruction, With Stenting of Meso‐Rex Bypass, to Successfully Manage Recurrent Portal Venous Flow Obstruction Post Segmental Liver Transplant in a Pediatric Patient

2025· article· en· W4412727769 on OpenAlexaff
Hayley Good, Vicky L. Ng, Asad Siddiqui, Blayne A. Sayed, Dimitri A. Parra

Bibliographic record

VenuePediatric Transplantation · 2025
Typearticle
Languageen
FieldMedicine
TopicLiver Disease and Transplantation
Canadian institutionsSickKids FoundationHospital for Sick ChildrenUniversity of Toronto
Fundersnot available
KeywordsMedicinePortal hypertensionBiliary atresiaPortosystemic shuntRadiologyLiver transplantationSurgeryAnastomosisStentAngioplastyStenosisInterventional radiologyTransplantationCirrhosisInternal medicine

Abstract

fetched live from OpenAlex

BACKGROUND: Portal vein complications can be difficult to manage in the context of challenging anatomy and porto-systemic collaterals. METHODS: This case illustrates a child with biliary atresia and associated laterality (situs inversus, polysplenia) features, who underwent segmental liver transplantation with portal venous conduit at 4 years of age for end-stage liver disease due to failed Kasai portoenterostomy. He subsequently developed portal venous conduit thrombosis requiring early surgical and interventional procedures. This was thought to be due to angulation of the conduit versus venous steal through multiple large portosystemic collaterals. Despite repeat angioplasty and embolization of portosystemic collaterals, he developed recurrent portal hypertension with upper gastrointestinal bleeding and persistent portal stenosis. Graft function remained well preserved. A meso-Rex bypass was therefore created 2-years 9-months post-transplant. Initial flow was excellent, but follow-up imaging revealed diminished flow and stricture at the left portal vein anastomosis. This was again thought to be secondary to steal through portosystemic collaterals and was refractory to angioplasty. Thus, a combined surgical-interventional radiology revision of the Meso-Rex bypass with laparotomy and liver mobilization, placement of an uncovered stent, portosystemic collaterals surgical ligation, and splenectomy of the main right-sided spleen was performed. RESULTS: There were no complications and, 2 years 8 months post procedure, there is excellent shunt patency and graft function with no signs of portal hypertension. CONCLUSION: This case report highlights the critical utility of a multidisciplinary approach and innovative solutions by an experienced program in the management of complex surgical complications following pediatric liver transplantation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.009
Threshold uncertainty score0.900

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.210
Teacher spread0.205 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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