The genetic basis of natural variation in sociability
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Sociability, defined as individuals' tendencies to affiliate with conspecifics, is widespread among animals, including species not traditionally categorized as social. A few studies have documented a positive association between sociability and fitness, and sociability has positive effects on health, well-being, and longevity in humans. Despite the importance of sociability, we still have limited information about its genetic basis. To address this knowledge gap, we compared gene expression in the heads of fruit flies (Drosophila melanogaster) from lineages artificially selected for, and divergent in, degree of sociability. We identified 174 genes that showed differential expression among low and high-sociability lineages, of which 33 genes have known effects on neuroanatomy, neurophysiology, or behavior. Experiments using knockdowns of 16 of the top candidate sociability genes revealed 6 of them significantly affecting sociability in the predicted direction. Relying on our large genomic database, we and others can further elucidate the genetic architecture and evolutionary biology of sociability.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it