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Record W4412753544 · doi:10.1016/j.cdnut.2025.107508

The Cost of Expanding Ethiopia’s Salt Iodization Program to Include Multiple Micronutrients

2025· article· en· W4412753544 on OpenAlexaff
Katherine P. Adams, Dawd Gashu, Elias Asfaw Zegeye, MG Venkatesh Mannar, Levente L. Diósady, N Ananth, E. Louise Ander

Bibliographic record

VenueCurrent Developments in Nutrition · 2025
Typearticle
Languageen
FieldMedicine
TopicFolate and B Vitamins Research
Canadian institutionsImpactUniversity of Toronto
FundersBill and Melinda Gates Foundation
KeywordsMicronutrientEnvironmental healthBusinessEnvironmental scienceMedicine

Abstract

fetched live from OpenAlex

Background: With near universal consumption of salt and technological advances that have made its fortification with multiple micronutrients feasible, salt has great potential for public health impact as a delivery vehicle for not only iodine but also multiple micronutrients. Decisions around modifying existing salt standards to include additional micronutrients should consider not only potential impacts but also stakeholder-specific costs. Objectives: We aimed to estimate the total and incremental cost of expanding Ethiopia's salt iodization program to include folic acid (dual fortified salt), folic acid and vitamin B-12 (triple fortified salt), or folic acid, vitamin B-12, and zinc (quadruple fortified salt). Methods: We developed activity-based cost models to estimate salt fortification costs over a 10-y time horizon (2024-2033). Model assumptions and parameters were primarily based on interviews with Ethiopian stakeholders in industry and government and nongovernmental partners. Results: The estimated annual average per capita cost of Ethiopia's existing salt iodization program was ∼$2.1 million (2021 US dollars) or ∼$7/metric ton (MT) of fortified salt (∼$0.02/y). Expanding the program to include folic acid, which could be sprayed onto salt along with the iodine, would increase the annual average per capita cost to ∼$2.5 million, or ∼$8.30/MT (∼$0.02/y). Annually, the costs of triple and quadruple fortified salt programs, which would require encapsulating the additional micronutrients as a solid premix to help ensure stability, were ∼$18 million (∼$59/MT; $0.13 per capita) and $19 million (∼$63/MT; ∼$0.14 per capita), respectively. Premix costs accounted for approximately half of the total cost of the iodized and dual fortified salt programs and ∼90% of triple and quadruple fortified salt. Conclusions: If Ethiopia considers modifying its existing salt iodization standard to include 1 or more additional micronutrients, there will be many important considerations, including costs and affordability. The cost estimates presented in this study can complement evidence of the potential for multiple fortified salt to reduce micronutrient deficiencies.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.693
Threshold uncertainty score0.364

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.038
GPT teacher head0.413
Teacher spread0.375 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designOther design
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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