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Record W4412760015 · doi:10.1186/s12891-025-09003-1

Preservation of the infrapatellar fat pad during total knee arthroplasty reduces subacute postoperative anterior knee pain: a randomized controlled trial

2025· article· en· W4412760015 on OpenAlexaboutno aff
Pruk Chaiyakit, Bunpreedee Petcharat, Ittiwat Onklin

Bibliographic record

VenueBMC Musculoskeletal Disorders · 2025
Typearticle
Languageen
FieldMedicine
TopicTotal Knee Arthroplasty Outcomes
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineInfrapatellar fat padRandomized controlled trialSports medicineOrthopedic surgeryTotal knee arthroplastyArthroplastyRheumatologyKnee painSurgeryAnterior knee painOsteoarthritisRehabilitationKnee surgeryPain medicinePhysical therapyAnesthesiaInternal medicineAnesthesiologyPatellaAlternative medicinePathology

Abstract

fetched live from OpenAlex

BACKGROUND: Preservation of the infrapatellar fat pad (IPFP) during total knee arthroplasty (TKA) is associated with a lower incidence of postoperative anterior knee pain (AKP). However, the comparative efficacy of IPFP preservation remains unclear. The objective of this randomized controlled trial (RCT) was to compare the incidence of AKP between IPFP preservation and partial excision of the IPFP. METHODS: This prospective RCT included patients with primary varus gonarthrosis < 20° who underwent unilateral computer-assisted TKA between March 2019 and November 2020. Patients were randomly assigned to the partial excision or preservation groups. The intraoperative and postoperative protocols were the same in each group. The incidence and severity of AKP, range of motion (ROM), and modified Western Ontario and McMaster Universities Arthritis Index (WOMAC) score were assessed at 1, 3, 6, and 12 months postoperatively and then annually thereafter. The pre- and postoperative Insall-Salvati ratio (ISR) and mechanical alignment (MA) were also evaluated. RESULTS: A total of 57 patients were included (27 in the partial excision group and 30 in the preservation group). At 1 month postoperatively, the preservation group had a significantly lower incidence of anterior knee pain (AKP) than the partial excision group (33.3% versus 77.8%, p = 0.001). The visual analogue scale (VAS) pain score was also significantly lower in the preservation group at 1 month (1.2 ± 2.0 vs. 2.4 ± 1.6, p < 0.05). However, these differences were not observed at later follow-up time points (3, 6, or 12 months). Modified WOMAC scores, range of motion (ROM), mechanical alignment (MA), and Insall-Salvati ratio (ISR) did not differ significantly between groups at any time point. Although a statistically significant difference in WOMAC score was observed at 6 months, the magnitude of this difference was below the minimal clinically important difference (MCID), indicating limited clinical relevance. CONCLUSION: IPFP preservation during TKA reduced the incidence and severity of subacute postoperative AKP. LEVEL OF EVIDENCE: I. Trial registration Thai Clinical Trials Registry, TCTR20220215011 Registered 08/02/2022 - Retrospectively registered, https://www.thaiclinicaltrials.org/show/TCTR20220215011 .

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.007
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.046
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.007
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.254
Teacher spread0.247 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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