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Record W4412765880 · doi:10.3389/frai.2025.1645467

AI-driven epidemic intelligence: the future of outbreak detection and response

2025· article· en· W4412765880 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueFrontiers in Artificial Intelligence · 2025
Typearticle
Languageen
FieldMedicine
TopicData-Driven Disease Surveillance
Canadian institutionsNational Research Council CanadaUniversity of Waterloo
FundersCanada Research Chairs
KeywordsComputer sciencePreparednessTransformative learningPandemicData scienceProcess (computing)Risk analysis (engineering)Computer securityInfectious disease (medical specialty)Coronavirus disease 2019 (COVID-19)BusinessMedicinePolitical sciencePsychologyDisease

Abstract

fetched live from OpenAlex

Epidemic intelligence, the process of detecting, verifying, and analyzing public health threats to enable timely responses, traditionally relies heavily on manual reporting and structured data, often causing delays and coverage gaps. The growing frequency of emerging infectious diseases highlights the urgency for more rapid and accurate surveillance methods. This perspective proposes a forward-looking conceptual framework for AI-driven epidemic intelligence, emphasizing the transformative potential of integrating large language models (LLMs), natural language processing (NLP), and optimization-based resource allocation strategies. While existing AI-driven systems have shown significant capabilities during the COVID-19 pandemic, several challenges remain, including real-time adaptability, multilingual data handling, misinformation, and public health policy alignment. To address these gaps, we propose an integrated, real-time adaptable LLM-based epidemic intelligence system, capable of correlating cross-source data, optimizing healthcare resource allocation, and supporting informed outbreak response. This approach aims to significantly improve early warning capabilities, enhancing forecasting accuracy, and strengthen pandemic preparedness.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.931
Threshold uncertainty score0.648

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.310
Teacher spread0.294 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it