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Record W4412765961 · doi:10.1002/smll.202503718

Nanomaterial‐Based Biosensors for Aflatoxin B1 Detection: Current Advances, Challenges, and Prospects

2025· review· en· W4412765961 on OpenAlexaff
Boyan Sun, Qiqi Wang, Sihan Wang, Pengpeng Lei, Tony Velkov, Gea Oliveri Conti, Jianzhong Shen, Haiyang Jiang, Chongshan Dai

Bibliographic record

VenueSmall · 2025
Typereview
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicAdvanced biosensing and bioanalysis techniques
Canadian institutionsUniversity of Waterloo
FundersBasic and Applied Basic Research Foundation of Guangdong ProvinceNatural Science Foundation of Beijing Municipality
KeywordsNanomaterialsNanotechnologyAflatoxinBiosensorRaw materialBiochemical engineeringMaterials scienceComputer scienceBiotechnologyChemistryBiologyEngineering

Abstract

fetched live from OpenAlex

Aflatoxins (AFTs) are mycotoxins recognized as the key contributors to environmental and food contamination. AFTs can contaminate food and raw materials at different phases of manufacturing, transformation, processing, distribution, and marketing. Aflatoxin B1 (AFB1) is the most harmful one among AFTs, and it exhibits potent toxic and carcinogenic effects in animals and humans. Currently, the efficient, fast, and sensitive methods for the early detection and monitoring of AFB1 in processed food and raw materials are urgently required. Nanomaterials, which possess unique physical, chemical, and optical properties, have gained increased traction in the manufacturing and improvement of biosensors for the detection sensitivity to AFB1. Herein, a comprehensive review of the development of nanomaterials-based biosensors for the detection of AFB1 in food and raw materials and their potential applications is provided. Additionally, the sensitivity, selectivity, and effectiveness in the detection of real samples are discussed. The biosensors aimed at AFB1 screening are highlighted using novel nanomaterials such as noble metal nanomaterials, quantum dots, and carbon-based nanomaterials. This review provides new information and insightful commentary, representing an important starting point for the future development and innovation of further innovative detection methods for AFB1 in food and raw materials.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.003
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0020.002
Science and technology studies0.0000.000
Scholarly communication0.0010.002
Open science0.0010.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0030.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.035
GPT teacher head0.326
Teacher spread0.291 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations12
Published2025
Admission routes1
Has abstractyes

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