Long-term survival in a dog with unresectable appendicular osteosarcoma treated with zoledronic acid plus carboplatin as palliative care
Bibliographic record
Abstract
Osteosarcoma (OSA) is the most common bone tumor in dogs. It is highly aggressive, and most patients die due to metastasis, especially to the lungs. This report showed the palliative care of an unresectable appendicular OSA in a 10-year-old neutered male Labrador Retriever dog. Amputation of the affected limb was not indicated due to obesity and bilateral hip dysplasia. For this reason, palliative care with carboplatin and zoledronic acid was proposed. The treatment was well tolerated and the owner reported improvement in the lameness and pain, resulting in a good quality of life. A survival time of 30 months (910 days) was observed. Treatment with zoledronic acid and carboplatin may be considered in cases of unresectable appendicular OSA because this treatment was safe and well tolerated.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".