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Record W4412805789 · doi:10.1016/j.cmpbup.2025.100211

Robust lung segmentation in Chest X-ray images using modified U-Net with deeper network and residual blocks

2025· article· en· W4412805789 on OpenAlexafffund
Wiley Tam, Paul Babyn, Javad Alirezaie

Bibliographic record

VenueComputer Methods and Programs in Biomedicine Update · 2025
Typearticle
Languageen
FieldMedicine
TopicCOVID-19 diagnosis using AI
Canadian institutionsUniversity of SaskatchewanUniversity of Toronto
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsResidualNet (polyhedron)SegmentationX-rayComputer scienceArtificial intelligenceMaterials scienceComputer visionMathematicsOpticsPhysicsGeometryAlgorithm

Abstract

fetched live from OpenAlex

Lung diseases remain a leading cause of mortality worldwide, as evidenced by statistics from the World Health Organization (WHO). The limited availability of radiologists to interpret Chest X-ray (CXR) images for diagnosing common lung conditions poses a significant challenge, often resulting in delayed diagnosis and treatment. In response, Computer-Aided Diagnostic (CAD) tools can be used to potentially streamline and expedite the diagnostic process. Recently, deep learning techniques have gained prominence in the automated analysis of CXR images, particularly in segmenting lung regions as a critical preliminary step. This study aims to develop and evaluate a lung segmentation model based on a modified U-Net architecture. The architecture leverages techniques such as transfer learning with DenseNet201 as a feature extractor alongside dilated convolutions and residual blocks. An ablation study was conducted to evaluate these architectural components, along with additional elements like augmented data, alternative backbones, and attention mechanisms. Numerous and extensive experiments were performed on two publicly available datasets, the Montgomery County (MC) and Shenzhen Hospital (SH) datasets, to validate the efficacy of these techniques on segmentation performance. Outperforming other state-of-the-art methods on the MC dataset, the proposed model achieved a Jaccard Index (IoU) of 97.77 and a Dice Similarity Coefficient (DSC) of 98.87. These results represent a significant improvement over the baseline U-Net, with gains of 3.37% and 1.75% in IoU and DSC, respectively. These findings highlight the importance of architectural enhancements in deep learning-based lung segmentation models, contributing to more efficient, accurate, and reliable CAD systems for lung disease assessment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.016
Threshold uncertainty score0.031

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.059
GPT teacher head0.379
Teacher spread0.320 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes2
Has abstractyes

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