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Record W4412815345 · doi:10.5376/jeb.2025.16.0005

The Role of the Creatine Phosphate System in Energy Storage and Release: From Molecular Mechanisms to Physiological Functions

2025· article· en· W4412815345 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

venuePublished in a venue whose home country is Canada.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueJournal of Energy Bioscience · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMuscle metabolism and nutrition
Canadian institutionsnot available
Fundersnot available
KeywordsCreatinePhosphateChemistryEnergy storageBiophysicsBiochemistryBiologyPhysicsThermodynamics

Abstract

fetched live from OpenAlex

The creatine phosphate system helps process energy in cells, especially in tissues that require a lot of energy and change quickly, such as muscles and brains. This study mainly talks about how the creatine phosphate system works, its basic principles, the pathways involved, and its role in the body. We focused on creatine kinase, which helps cells regenerate ATP, and also plays a role in "storing" energy, and is even responsible for transmitting energy to where it is needed. This process is very critical during muscle contraction and brain function, especially in those organs that use a lot of energy, it can help cells maintain a stable energy state. The article also mentioned that supplementing creatine phosphate may help some diseases, such as muscle diseases and neurodegenerative diseases. Now, because of the increasing advancement of technologies such as molecular imaging and bioinformatics, people have a deeper understanding of how creatine is metabolized and how it cooperates with other cellular processes. In the future, researchers may try to develop some new therapies related to creatine. We will continue to explore how it is regulated at the molecular level and see how it is related to other metabolic pathways. These studies are expected to bring new ideas and treatments for treating some energy-related diseases.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.027
Threshold uncertainty score0.157

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.003
GPT teacher head0.197
Teacher spread0.194 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it