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Record W4412815345 · doi:10.5376/jeb.2025.16.0005

The Role of the Creatine Phosphate System in Energy Storage and Release: From Molecular Mechanisms to Physiological Functions

2025· article· en· W4412815345 on OpenAlexvenueno aff
Wenying Hong, Wen Huang

Bibliographic record

VenueJournal of Energy Bioscience · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMuscle metabolism and nutrition
Canadian institutionsnot available
Fundersnot available
KeywordsCreatinePhosphateChemistryEnergy storageBiophysicsBiochemistryBiologyPhysicsThermodynamics

Abstract

fetched live from OpenAlex

The creatine phosphate system helps process energy in cells, especially in tissues that require a lot of energy and change quickly, such as muscles and brains. This study mainly talks about how the creatine phosphate system works, its basic principles, the pathways involved, and its role in the body. We focused on creatine kinase, which helps cells regenerate ATP, and also plays a role in "storing" energy, and is even responsible for transmitting energy to where it is needed. This process is very critical during muscle contraction and brain function, especially in those organs that use a lot of energy, it can help cells maintain a stable energy state. The article also mentioned that supplementing creatine phosphate may help some diseases, such as muscle diseases and neurodegenerative diseases. Now, because of the increasing advancement of technologies such as molecular imaging and bioinformatics, people have a deeper understanding of how creatine is metabolized and how it cooperates with other cellular processes. In the future, researchers may try to develop some new therapies related to creatine. We will continue to explore how it is regulated at the molecular level and see how it is related to other metabolic pathways. These studies are expected to bring new ideas and treatments for treating some energy-related diseases.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.002
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.002
Scholarly communication0.0020.004
Open science0.0010.002
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.003
GPT teacher head0.197
Teacher spread0.194 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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