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The Effectiveness of Adding High-Intensity Laser Therapy (HILT) to Physical Exercise in Reducing Pain, Improving Muscle Strength, and Enhancing Functional Ability in Patients with Knee Osteoarthritis: A Randomized Controlled Trial

2025· article· en· W4412819969 on OpenAlexaboutno aff
Laksmana Rizki, Tirza Z. Tamin, Fitri Anestherita, Harrison Handoko

Bibliographic record

VenueJournal Of The Indonesian Medical Association · 2025
Typearticle
Languageen
FieldMedicine
TopicLaser Applications in Dentistry and Medicine
Canadian institutionsnot available
FundersFakultas Kedokteran, Universitas IndonesiaUniversitas Indonesia
KeywordsOsteoarthritisPhysical therapyRandomized controlled trialMedicinePhysical medicine and rehabilitationIntensity (physics)Muscle strengthAlternative medicineSurgeryPathology

Abstract

fetched live from OpenAlex

Introduction: Osteoarthritis (OA) is a leading cause of disability worldwide, impacting patient’s daily functional abilities as well as quality of life due to chronic pain associated with joint damage. High-Intensity Laser Therapy (HILT) has been proven effective in reducing pain and improving function in patients with knee OA. Despite its recognition as a safe and effective modality, standardized protocols for its use in knee OA are lacking. This study aims to evaluate the effectiveness of incorporating HILT in addition to physical exercise programs for patients with knee OA.Methods: 30 patients with knee OA were randomized into 2 groups, HILT + physical exercise (intervention group), and physical exercise only (control group). Visual Analogue Scale (VAS), quadriceps and hamstring muscle strength using exercise testing, and functional ability using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire were measured and compared.Result: Both groups displayed statistically significant improvement in pain, muscle strength, and functional ability by the end of the program (week 4) compared to the initial examination (p less than 0.05). When compared, there was a significant difference in pain reduction and functional ability in favor of the intervention group (p less than 0.05). However, there were no significant differences in quadriceps and hamstring muscle strength between the groups (p=0.148 and p=0.345, respectively).Conclusion: In this study, it was shown that the combination of HILT and physical exercise was more effective in alleviating pain and enhancing functional ability in patients with knee OA compared to physical exercise alone.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.023

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.003
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0050.004
Bibliometrics0.0010.001
Science and technology studies0.0010.002
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0030.003
Insufficient payload (model declined to judge)0.0070.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.002
GPT teacher head0.224
Teacher spread0.221 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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