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Record W4412866057 · doi:10.1016/j.ajt.2025.07.1787

Optimizing CMV Management in Lung Transplantation: A Modified Delphi Method to Address Complex Challenges

2025· article· en· W4412866057 on OpenAlexaff
D. Levine, Linda Snyder, Atul Humar, L. Danziger-Isakov, S. Juvet, Camille N. Kotton

Bibliographic record

VenueAmerican Journal of Transplantation · 2025
Typearticle
Languageen
FieldMedicine
TopicTransplantation: Methods and Outcomes
Canadian institutionsUniversity Health NetworkToronto General Hospital
Fundersnot available
KeywordsMedicineLung transplantationTransplantationIntensive care medicineDelphiLungDelphi methodSurgeryInternal medicineArtificial intelligence

Abstract

fetched live from OpenAlex

Purpose: International guidelines for CMV management in solid organ transplantation, first published in 2010 and periodically updated, have contributed significantly to standardizing and enhancing CMV-related care. However, significant evidence gaps remain. In lung transplantation, where CMV poses a substantial risk, consensus is still lacking in multiple important realms, some of which would be challenging to answer via clinical trials. Our study aims to identify and address these gaps using a Modified Delphi Method.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.073
metaresearch head score (Gemma)0.078
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.073
Threshold uncertainty score0.384

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0730.078
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0030.002
Science and technology studies0.0030.002
Scholarly communication0.0030.003
Open science0.0010.007
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0080.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.053
GPT teacher head0.391
Teacher spread0.339 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractno

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