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Record W4412869862 · doi:10.1136/bmjopen-2025-102143

Evaluating an early childhood caries prevention strategy: a study protocol for a stepped-wedge cluster randomised controlled trial

2025· article· en· W4412869862 on OpenAlexaff
Peiya Cao, Yan Zhang, Shannon H. Houser, Jinming Yang, Wenjuan Tao, Fan Zhang, Wei Yin, Xing Qu

Bibliographic record

VenueBMJ Open · 2025
Typearticle
Languageen
FieldDentistry
TopicDental Health and Care Utilization
Canadian institutionsYork University
FundersNational Natural Science Foundation of China
KeywordsMedicineProtocol (science)Cluster randomised controlled trialCluster (spacecraft)Randomized controlled trialBiostatisticsClinical trialPublic healthFamily medicinePediatricsAlternative medicineSurgeryNursingInternal medicinePathology

Abstract

fetched live from OpenAlex

INTRODUCTION: Caries risk assessment and management (CRAM) conducted by primary care providers is critical for preventing early childhood caries. Yet, the implementation of these preventive strategies remains understudied in low- and middle-income countries. This study aims to evaluate the implementation and effectiveness of a CRAM intervention in Chinese primary care settings. METHODS AND ANALYSIS: We will conduct a hybrid type II stepped-wedge cluster randomised controlled trial across nine primary healthcare institutions in Luzhou City, China. Institutions will be randomly allocated into three intervention waves. Primary care providers will be trained to deliver CRAM. The two primary outcomes are (1) the proportion of primary care providers completing all CRAM procedures and (2) improvements in parents' home-based oral care practices for children under age 3. Secondary outcomes include children's oral health-related quality of life, time to first caries incidence, and the cost-effectiveness of the intervention. Qualitative interviews will explore barriers and facilitators to implementation. ETHICS AND DISSEMINATION: The study protocol has received approval from the Ethics Committee of West China Hospital, Sichuan University. Study findings will be disseminated through peer-reviewed journal publications and presentations at academic conferences. Research summaries and policy briefs will be developed for key stakeholders and decision-makers at the local, provincial and national levels. TRIAL REGISTRATION NUMBER: ChiCTR2400090741.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.085
metaresearch head score (Gemma)0.069
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Protocol · Consensus signal: Protocol
Teacher disagreement score0.085
Threshold uncertainty score0.452

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0850.069
Meta-epidemiology (narrow)0.0070.004
Meta-epidemiology (broad)0.0130.007
Bibliometrics0.0040.006
Science and technology studies0.0040.005
Scholarly communication0.0060.005
Open science0.0050.003
Research integrity0.0090.009
Insufficient payload (model declined to judge)0.0770.011

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.147
GPT teacher head0.538
Teacher spread0.391 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designRandomized trial
Domainnot available
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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