Robust Segmentation of Lung Proton and Hyperpolarized Gas MRI with Vision Transformers and CNNs: A Comparative Analysis of Performance Under Artificial Noise
Bibliographic record
Abstract
Accurate segmentation in medical imaging is essential for disease diagnosis and monitoring, particularly in lung imaging using proton and hyperpolarized gas MRI. However, image degradation due to noise and artifacts-especially in hyperpolarized gas MRI, where scans are acquired during breath-holds-poses challenges for conventional segmentation algorithms. This study evaluates the robustness of deep learning segmentation models under varying Gaussian noise levels, comparing traditional convolutional neural networks (CNNs) with modern Vision Transformer (ViT)-based models. Using a dataset of proton and hyperpolarized gas MRI slices from 56 participants, we trained and tested Feature Pyramid Network (FPN) and U-Net architectures with both CNN (VGG16, VGG19, ResNet152) and ViT (MiT-B0, B3, B5) backbones. Results showed that ViT-based models, particularly those using the SegFormer backbone, consistently outperformed CNN-based counterparts across all metrics and noise levels. The performance gap was especially pronounced in high-noise conditions, where transformer models retained higher Dice scores and lower boundary errors. These findings highlight the potential of ViT-based architectures for deployment in clinically realistic, low-SNR environments such as hyperpolarized gas MRI, where segmentation reliability is critical.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.005 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".