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Record W4412950197 · doi:10.1093/jme/tjaf068

Exploring factors affecting the reintroduction and amplification of West Nile virus in heterogeneous landscapes in Canada, using a cellular automata approach

2025· article· en· W4412950197 on OpenAlexaffabout
Baki Cissé, David R. Lapen, Karine Chalvet‐Monfray, Nicholas H. Ogden, Antoinette Ludwig

Bibliographic record

VenueJournal of Medical Entomology · 2025
Typearticle
Languageen
FieldMedicine
TopicMosquito-borne diseases and control
Canadian institutionsAgriculture and Agri-Food CanadaUniversité de MontréalCegep de Saint HyacinthePublic Health Agency of Canada
Fundersnot available
KeywordsOverwinteringBiologyOutbreakPopulationWest Nile virusBiological dispersalVector (molecular biology)Bird migrationEcologyVirusMetapopulationCulexPersistence (discontinuity)ZoologyVirologyDemographyGenetics

Abstract

fetched live from OpenAlex

West-Nile virus (WNV) is an endemic public health risk in Canada, with outbreaks/reintroduction and amplification that may increase in frequency and size with climate change and urbanization. In this modeling study, we used a compartmentalized and spatialized Susceptible, Exposed, Infected, Recovered (SEIR) WNV transmission model incorporating a cellular automata approach. We tested four scenarios in which we modified the number of infected birds arriving in spring, modified the number of infected mosquitoes emerging from their overwintering/dormancy period, studied the impact of bird abundance on epidemic starting point locations, and examined the progressive shift in mosquito feeding preferences from birds to mammals. First, we observed that WNV amplification may be associated with the arrival of infected migratory birds in the spring, with more severe epidemics as the number of infected birds increases. Secondly, amplification due to the local persistence of WNV virus in surviving infected overwintering female mosquitoes resulted in more severe epidemics in the human population than when amplification was due to the arrival of infected birds. Thirdly, epidemics were more severe when initiated in cells with low bird density than in those with high density. Lastly, the shift in mosquito feeding preference to human blood meals at the end of summer could generate more cases in human populations if reservoir birds delay their migration and stay longer, amplifying the virus locally. A field study is needed to quantify the impact of these mechanisms on WNV reintroduction in southeastern Canada, to better design interventions and early warning systems.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.145
Threshold uncertainty score0.945

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.043
GPT teacher head0.283
Teacher spread0.239 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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