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Record W4412987884 · doi:10.1101/2025.08.04.668381

Noisy neural systems with static and dynamic Hopf bifurcation parameters

2025· preprint· en· W4412987884 on OpenAlexaff
Priscilla E. Greenwood, Lawrence M. Ward

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2025
Typepreprint
Languageen
FieldNeuroscience
TopicNeural dynamics and brain function
Canadian institutionsVancouver Coastal HealthUniversity of British Columbia
Fundersnot available
KeywordsHopf bifurcationBifurcationBiological applications of bifurcation theoryComputer scienceNeural systemControl theory (sociology)Artificial intelligencePhysicsNonlinear systemPsychologyNeuroscience

Abstract

fetched live from OpenAlex

Abstract Stochastic neural oscillations may be quasi-cycles or stochastic limit cycles. Here we discuss how and when these arise in stochastic dynamical systems with Hopf bifurcations, and point to relevant mathematical results. We describe a new type of oscillation, quasi-limit-cycles, which are limit cycles stirred up by noise during time periods called ‘bifurcation delays’ in deterministic models. We define a class of models of neural activity all of which display Hopf bifurcations in their base (fixed bifurcation parameter) deterministic form. We then introduce a two-time, slow-fast, version of our model class, in which the bifurcation parameter, instead of being fixed, changes on a time scale slower than the time scale of the state variables. We demonstrate the effects of the slowly changing bifurcation parameter on the deterministic dynamics of the state variables, in particular ‘delayed bifurcation.’ We find a new understanding about the length of the delay. Most importantly, we display with simulations the effect of noise on the dynamics of both base system and slow-fast system models in our class. Adding noise to a slow-fast model eliminates the bifurcation delay and induces what we call ‘quasi-limit-cycles’ during the delay period. We measure the sizes of the quasi-limit-cycles and show that they are closely related to the sizes of the limit cycles that would arise from the same values of the bifurcation parameter in the deterministic base system. We conclude that, given the similarities of the dynamics of these models under moderate noise, there is little reason to favour one model over another when studying the behaviour of large groups of neurons, i.e., when used as neural mass models. Author summary Recordings of brain activity display noisy periodic oscillations. Many computational models of this oscillatory activity have what is called a ‘Hopf bifurcation.’ This is a point in the dynamic phase space at which solutions to the deterministic versions of the models change from having a stable fixed point to having a stable limit cycle. In this paper we define a new class of models of oscillatory brain activity all of which have Hopf bifurcations. We compute both deterministic and stochastic path solutions to the models. These solutions give additional insight into an intriguing phenomenon of these models when a parameter slowly changes, called ‘delayed bifurcation,’ as well as expanding our knowledge of their stochastic dynamics. In particular, we define and measure a new type of noisy oscillation, called ‘quasi-limit-cycles,’ that occur during a bifurcation delay in stochastic solutions. The stochastic versions of these models are roughly equally useful as neural mass models.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.219
Teacher spread0.204 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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