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Record W4413010725 · doi:10.1109/tmi.2025.3596247

Collaborative Learning of Augmentation and Disentanglement for Semi-Supervised Domain Generalized Medical Image Segmentation

2025· article· en· W4413010725 on OpenAlexaff
Zhiqiang Shen, Peng Cao, Qinghua Zhou, Jinzhu Yang, Osmar R. Zai͏̈ane

Bibliographic record

VenueIEEE Transactions on Medical Imaging · 2025
Typearticle
Languageen
FieldComputer Science
TopicMedical Image Segmentation Techniques
Canadian institutionsUniversity of Alberta
FundersFundamental Research Funds for the Central UniversitiesChina Scholarship CouncilNatural Science Foundation of Liaoning ProvinceNational Natural Science Foundation of China
KeywordsImage segmentationSegmentationArtificial intelligenceComputer scienceImage (mathematics)Domain (mathematical analysis)Computer visionMedical imagingScale-space segmentationPattern recognition (psychology)Mathematics

Abstract

fetched live from OpenAlex

This paper explores a challenging yet realistic scenario: semi-supervised domain generalization (SSDG) that includes label scarcity and domain shift problems. We pinpoint that the limitations of previous SSDG methods lie in 1) neglecting the difference between domain shifts existing within a training dataset (intra-domain shift, IDS) and those occurring between training and testing datasets (cross-domain shift, CDS) and 2) overlooking the interplay between label scarcity and domain shifts, resulting in these methods merely stitching together semi-supervised learning (SSL) and domain generalization (DG) techniques. Considering these limitations, we propose a novel perspective to decompose SSDG into the combination of unsupervised domain adaptation (UDA) and DG problems. To this end, we design a causal augmentation and disentanglement framework (CausalAD) for semi-supervised domain generalized medical image segmentation. Concretely, CausalAD involves two collaborative processes: an augmentation process, which utilizes disentangled style factors to perform style augmentation for UDA, and a disentanglement process, which decouples domain-invariant (content) and domain-variant (noise and style) features for DG. Furthermore, we propose a proxy-based self-paced training strategy (ProSPT) to guide the training of CausalAD by gradually selecting unlabeled image pixels with high-quality pseudo labels in a self-paced training manner. Finally, we introduce a hierarchical structural causal model (HSCM) to explain the intuition and concept behind our method. Extensive experiments in the cross-sequence, cross-site, and cross-modality semi-supervised domain generalized medical image segmentation settings show the effectiveness of CausalAD and its superiority over the state-of-the-art. The code is available at https://github.com/Senyh/CausalAD.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.917
Threshold uncertainty score0.762

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.312
Teacher spread0.305 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designOther design
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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