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Record W4413018908 · doi:10.1371/journal.pone.0329325

Economics of vaccination against diarrhoea and respiratory diseases in French cow calves’ systems: A modelling approach

2025· article· en· W4413018908 on OpenAlexaff
Ahmed Ferchiou, Anthony Giacomini, Nicolas Herman, Guillaume Lhermie, Didier Raboisson

Bibliographic record

VenuePLoS ONE · 2025
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicAnimal Disease Management and Epidemiology
Canadian institutionsUniversity of Calgary
Fundersnot available
KeywordsVaccinationMedicineEnvironmental healthBreedHerdVeterinary medicineHerd immunityBiologyAnimal scienceImmunology

Abstract

fetched live from OpenAlex

To assess the economic benefits of vaccination against diarrhoea and respiratory diseases in cow-calf systems, a stochastic mechanistic mathematical programming bio-economic model was developed for a beef Charolais breed farm. The model reproduced herd dynamics on a weekly basis over a 10-year period, including animal growth, reproduction and diseases risks and control (treatments and vaccination). Three baseline risk levels of diarrhoea and respiratory disease were considered to simulate low, average, and high infection risks on the farm. The results demonstrated the model's ability to reproduce average farm dynamics, with diarrhoea prevalence ranging from 8% to 33% and respiratory diseases from 13% to 79%. On average, prevalences were decreased by 24% and 50%, respectively, due to vaccination, which also reduced the 2-day to 1-month mortality rates by 2-3% and 15-17%, respectively. The net value of vaccination was positive except in cases of low infection risk of diarrhoea and respiratory diseases: the return on investment (ROI) of vaccination was 0.4-0.5 (€1 invested yields €0.4-0.5) in the baseline scenario (middle infection risks), negative under low infection risks, and reached 1 (€1 invested yields €1) for high infection risks. The results also showed that farmers may earn €58-75 in additional revenue per extra hour of labour dedicated to vaccination in the medium-risk scenario. Despite the limited availability of data for cow-calf systems, this study demonstrated the economic benefit of vaccination in most combinations of scenarios and risks. The profitability of vaccination was challenged when low disease risks were considered, but in such cases, vaccination may serve as insurance against financial losses in case of health status deterioration.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.072
Threshold uncertainty score0.143

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0020.001
Open science0.0010.001
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.065
GPT teacher head0.215
Teacher spread0.150 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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