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Modeled Carbon Footprint of Change of Sterile Gloves and Instruments for Abdominal Wound Closure

2025· article· en· W4413020622 on OpenAlexaff
Virginia Ledda, Adesoji Ademuyiwa, Adewale Adisa, Aneel Bhangu, Parvez Haque, J.C. Allen Ingabire, Faustin Ntirenganya, Maria Picciochi, Atul Suroy, Robert Lillywhite, Dmitri Nepogodiev, Ahmed Abdisamed, Adamu Issaka, AHMED ALBAGIR ALI ALTAYYEB, Ahmed Mekki, Aidan Bannon, Aikaterini Karakonstanti, Aime Dieudonne Hirwa, Albaro José Nieto‐Calvache, Alejandro González‐Ojeda, Alfie J. Kavalakat, Amar Odedra, Amman Malik, Andrea Nickeas, Andrew R. L. Stevenson, Andrey Litvin, Angelika Kaufmann, Anil Luther, Anis Hasnaoui, Anisa Kushairi, Anja Imsirovic, A. Robinson, Antonio Pérez Ferrer, Antonio Ramos De-la-Medina, A. Shaji George, April Camilla Roslani, Aristeidis Papadopoulos, Arun Sahni, Ashish Chaudhrie, Ashly Thomas, Ayesha Bibi, Bashir Abobaker Albakosh, Binay Kumar, Branko Bogdanić, Bruno Nardo, Caitlin W. Brennan, Cara Hatcher, Carolina Moreno Licea, Caroline Wilburn, Catriona Frankling, Chamaidi Sarakatsianou, Chinar Goyal, CHARITAKI EVGENIA, Chris J Smart, Chris Agbo, Christian Udu Ngwu, Christiana Osei-Dwomoh, Christopher Aboah, Claudia Castellanos, Cleo Kenington, Clotilde Fuentes Orozco, Cortland Linder, CYNTHIA AYODEJI AGBONROFO, Deena Harji, Deepak Jain, Deepak Singh, Dimitrios Spinos, Djifid Morel Séto, Dmitry Mikhailovich Adamovich, Dorothy Kufeji, Doug Bowley, Abubakar Bala Muhammad, Narendra Siddaiah, S.S. Jakhar, Dragana Živković, Ebenezer Kwame Amofa, Ebere Ugwu, Elisa Paoluzzi Tomada, Elizabeth Li, Elizabeth Westwood, Emmanuel Aadereyir Nachelleh, Emmet Dorrian, Eseenam Agbeko, Ewen M. Harrison, Fahed Gareb, Fareeda Galley, Fennie Sam, Feriha Fatima Khidri, Francesco Pata, Gianluca Pellino, Gonzalo Delgado-Hernández, Guillermo Yanowsky Reyes, Gustavo M. Machaín, H.I. Hanafi, Hadijat Olaide Raji, Helen van Vliet, Helen Suttenwood, Hesham Abozied, Hesham Zalghana, Hugh Montgomery, Humaira Hussain, Ibrahim Adel Hamdoun, Ifeanyichukwu Ugwu, Imtiaz Wani, Iniesta aurelie, Isam Bsisu, Ismaïl Lawani, Ian Seddon, Jam Nazeer Ahmad, James Glasbey, Jane Barnard, Jayan Dewantha Jayasinghe, Jennifer Kirkby, James E. Ip, Jessica Fleminger, Joël L. Lavanchy, John Tabiri Abebrese, Jon Lacy‐Colson, Jonathan Lee, Jonathan P Evans, Katherina McEvoy, Kethy FAGNON, Khaled Mohammed Al‐Sayaghi, Konstancja Tadrak, Kriscia Vanessa Ascencio Diaz, Lanre Lamid, Laura Ballance, Lofty‐John Anyanwu, Lovenish Bains, Ludger Barthelmes, Luke Nicholson, Madushika Rajapakse, Margot Flint, Mario Jesús Guzmán Ruvalcaba, Mark Cheetham, Marta Wachtl, Massimiliano Veroux, Matthew D. Gardiner, Matthew Popplewell, Michelle Spiteri, Miguel Gasakure, Minale Merene, Moath Ahmed Abdullah Almuradi, Mohamed A. Thaha, Mohamed Ghula, M. Marar, Mohammed Sheriff, Mohammed Aliyu, Montassar Ghalleb, Moses Dokurugu, Muhammad Fairuz Shah Abd Karim, Mohammed Ismail, Muhammad Mudasir Khan, Navneet Kumar Chaudhary, Nick Battersby, Nnaemeka Nwafulume, Omolara Williams, Pariza Gupta, Patrick Sharman, Paul Marriott, Paul S. Robinson, Peter Agbonrofo, Peter Paal, Rachel Sam, Rahel Assefa, Raja Haseeb Basit, Rajive Jose, Rajkumar KS, Ramanpreet Kaur, Rasiah Bharathan, Reddy Abhinaya P, Robert K. Parker, Robert Whitham, Rohin Mittal, romain Letartre, Romy Kenyon, Rory Kokelaar, Ross Lathan, Ross Coomber, Ruzaimie Noor, Salih Al-Ani, Saminu Muhammad, Samson Olori, Samuel Ali Sani, Samuel Kwame Amoako Asirifi, Sanjay Pandanaboyana, Setthasorn Zhi Yang Ooi, Shireen Anne Nah, Simon Clarke, Sonia Bhangu, Sonia Mathai, Soyombo Orsoo, Spiros Delis, Stefan Welter, Stelian Ştefăniţă Mogoantă, Stephen G Gana, Suraiya Auwal Suleiman, Taiye Taibat Ibiyeye, Tariq Alhammali, Theophilus Teddy Kojo Anyomih, Theophilus Justus Kofi Adjeso, Thida Oung, Tom Challoner, Tosin Akinyemi, Upamanyu Nath, V Pollet, Vairavan Narayanan, Vandana chaukar, Vasanthika Thuduvage, Weerakkodige Mithun Chamindaka Alwis, Wegene Tadesse Shenkutie, Yousuf Sabah, Zahra Hussain

Bibliographic record

VenueJAMA Network Open · 2025
Typearticle
Languageen
FieldMedicine
TopicSurgical site infection prevention
Canadian institutionsCentre for Global Health Research
Fundersnot available
KeywordsCarbon footprintRandomized controlled trialMedicineFootprintIntervention (counseling)Greenhouse gasEnvironmental scienceSurgeryGeographyNursingEcology

Abstract

fetched live from OpenAlex

Importance: The Cheetah randomized trial demonstrated that changing sterile gloves and instruments before wound closure reduces surgical site infections (SSI) in abdominal surgery. However, its environmental impact remains unclear. Objectives: To estimate the global carbon footprint associated with changing sterile gloves and instruments before closure abdominal wound. Design, Setting, and Participants: This decision analytic model compared the carbon footprint of a glove and instrument change intervention against a control (no glove and instrument change). Model parameters were sourced from a large cluster randomized trial conducted in 7 low- and middle-income countries (LMICs) between June 2020 and March 2022, as well as data from stakeholder engagement and existing research. Boundaries included the trial intervention and in-hospital resources used to manage SSI. The analysis was stratified by wound contamination status (clean-contaminated, contaminated-dirty) and country-income classification. Main Outcome and Measures: Average per-patient wound-specific carbon footprint, calculated as the sum of the carbon footprint of glove and instrument change and SSI. Sensitivity analyses were based on the lowest and highest possible values for key model parameters: intervention effectiveness, intervention carbon footprint, and SSI carbon footprint. The best-case analysis was based on highest possible intervention effectiveness, lowest possible intervention carbon footprint, highest possible SSI carbon footprint. The worst-case analysis was based on lowest intervention effectiveness, highest intervention carbon footprint, and lowest SSI carbon footprint. Results: In LMICs, the difference in carbon footprints between the intervention and control groups was 10.97 kg CO2 equivalents (kgCO2e) (scenario range, -2.53 to 33.50 kgCO2e) for clean-contaminated and 22.60 kgCO2e (scenario range, -1.62 to 61.17 kgCO2e) for contaminated-dirty surgeries. In high-income countries, differences were 4.14 kgCO2e (scenario range, -3.38 to 17.95 kgCO2e) and 10.48 kgCO2e (scenario range, -3.06 to 37.62 kgCO2e), respectively. Country-level modeling found the intervention to be consistently associated with a lower wound-specific carbon footprint across all countries. Conclusions and Relevance: In this decision analytic model, sterile glove and instrument change before wound closure was associated with a reduced wound-specific carbon footprint across all country income settings. Alongside clinical and economic benefits, this intervention may support more sustainable surgical care; national associations and governments should consider its adoption to improve outcomes for both patients and the planet.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.007
metaresearch head score (Gemma)0.013
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.023
Threshold uncertainty score0.045

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0070.013
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.004
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0020.001
Open science0.0020.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0080.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.064
GPT teacher head0.349
Teacher spread0.285 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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