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Record W4413024686 · doi:10.1111/anae.16709

Trends in greenhouse gas emissions from volatile anaesthetics in 41 countries: 2013–2023

2025· article· en· W4413024686 on OpenAlexaboutno aff
Marta Caviglia, Andrealuna Ucciero, Andrea Conti, Aurora Di Filippo, Francesco Trotta, Luca Ragazzoni, Francesco Della Corte, Francesco Barone‐Adesi

Bibliographic record

VenueAnaesthesia · 2025
Typearticle
Languageen
FieldEnvironmental Science
TopicClimate Change and Health Impacts
Canadian institutionsnot available
Fundersnot available
KeywordsGreenhouse gasPer capitaCarbon dioxideMedicineEnvironmental scienceEuropean unionCarbon dioxide equivalentEnvironmental protectionPopulationEnvironmental healthNatural resource economicsToxicologyAgricultural economicsBusinessInternational tradeEconomics

Abstract

fetched live from OpenAlex

INTRODUCTION: Inhalational anaesthetics contribute to greenhouse gas emissions, leading to regulatory restrictions in some countries. This study analysed time trends of greenhouse gas emissions directly attributable to the use of volatile anaesthetic agents in 41 countries. METHODS: Sales data were obtained using data from IQVIA MIDAS® and national medicines agencies. We calculated the kilograms of carbon dioxide equivalents (based on global warming potential) per capita and percentage change in greenhouse gas emissions, from the emission of volatile anaesthetics from 2018 to 2023. RESULTS: Data were obtained for 41 countries, representing approximately 35% of the global population. Greenhouse gas emissions associated with volatile anaesthetic agents decreased in the 27 European Union nations and other 'western' countries included in the study (Australia, Canada, New Zealand, UK and USA), achieving in some cases below 0.5 kg of carbon dioxide equivalents per inhabitant. In contrast, several Asian countries showed a substantial increase in emissions, with South Korea and Japan reporting the highest values globally (approximately 2.5 kg of carbon dioxide equivalents per inhabitant). A secondary analysis restricted to European countries showed a 17-fold difference in per-capita carbon-equivalent emissions between the highest and lowest emitters, suggesting that recommendations on the use of volatile anaesthetic agents are implemented inconsistently. DISCUSSION: Our study highlighted large differences in the management of greenhouse gas emissions attributable to volatile anaesthetic use. While results show a decreasing trend in western countries, albeit with substantial variation, rising trends observed in many Asian countries may constitute a source of concern. The experience of nations that have phased out the highest impacting volatile anaesthetic agents show that reducing emissions below 0.5 kg of carbon dioxide equivalents per inhabitant is attainable. This should serve as a model for other systems, prompting implementation of educational initiatives and specific policies.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.084
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.298
Teacher spread0.271 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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