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Record W4413037056 · doi:10.1136/bmjoq-2025-003400

Metabolic monitoring among patients with psychotic disorders taking antipsychotics: results of a quality improvement project to address this challenging guideline-practice gap

2025· article· en· W4413037056 on OpenAlexafffundabout
Yomen Al-Saati, Ethiraj Vijayakumar, Christine Leong, Jennifer Hensel, Nina Kuzenko

Bibliographic record

VenueBMJ Open Quality · 2025
Typearticle
Languageen
FieldMedicine
TopicSchizophrenia research and treatment
Canadian institutionsUniversity of Manitoba
FundersAgency for Healthcare Research and QualityUniversity of Manitoba
KeywordsGuidelineMedicineMetabolic syndromeAntipsychoticSchizophrenia (object-oriented programming)PsychiatryInternal medicineObesity

Abstract

fetched live from OpenAlex

BACKGROUND: Metabolic adverse effects of antipsychotic medications pose significant health risks for patients with psychotic disorders. Despite clinical practice guidelines recommending regular metabolic monitoring, adherence to these recommendations remains suboptimal in psychiatric settings. OBJECTIVE: This quality improvement project aimed to assess the impact of an organisational paper-based metabolic monitoring form (MMF) on monitoring practices for patients with psychotic disorders receiving antipsychotic medications at an outpatient psychiatric clinic in a large Canadian city. METHODS: A pre-post intervention study was carried out to assess the impact of the MMF on annual monitoring among 75 randomly selected eligible patients. Metabolic monitoring parameters (blood pressure, weight, waist circumference and glucose and lipid profiles) were reviewed 1 year before and after the introduction of the form. RESULTS: The MMF was missing from 10 charts, and despite its presence in the remainder, no improvement was observed in metabolic parameter documentation, and overall guideline adherence remained low. Fasting glucose and HbA1c measurements were most frequently ordered, while blood pressure and weight measurements remained consistently low across both periods. CONCLUSIONS: The implementation of a paper-based MMF alone was insufficient to bridge the guideline-practice gap in metabolic monitoring, highlighting the need for other or concurrent strategies to achieve improvement.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.005
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.541
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0050.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.137
GPT teacher head0.499
Teacher spread0.363 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes3
Has abstractyes

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