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Record W4413055126 · doi:10.1080/14737175.2025.2542759

Electroconvulsive therapy in patients with trauma and personality disorders: what is the evidence?

2025· review· en· W4413055126 on OpenAlexaff
Jeanette Hui, Caroline Wanderley Espinola, Terri Rodak, Daniel M. Blumberger

Bibliographic record

VenueExpert Review of Neurotherapeutics · 2025
Typereview
Languageen
FieldMedicine
TopicElectroconvulsive Therapy Studies
Canadian institutionsMcMaster UniversityUniversity of TorontoCentre for Addiction and Mental Health
Fundersnot available
KeywordsElectroconvulsive therapyBorderline personality disorderPsycINFOPersonality disordersPsychiatryComorbidityClinical psychologyMood disordersPsychologyMajor depressive disorderPsychological interventionRandomized controlled trialMoodPersonalityMedicineMEDLINEAnxietySchizophrenia (object-oriented programming)Internal medicine

Abstract

fetched live from OpenAlex

INTRODUCTION: Electroconvulsive therapy (ECT) is one the most effective interventions for treatment-resistant depression. There is a link between trauma history and the development of depression, and frequent comorbidity with post-traumatic stress disorder (PTSD) and personality disorders. The impact of comorbid trauma and personality disorders on the efficacy of ECT has attracted research interest, with the possibility raised for using ECT to target other core symptoms of these disorders. AREAS COVERED: In this scoping review, the authors describe the available evidence on the use of ECT in personality disorders, PTSD, and individuals with a trauma history. The article is based on literature derived from Embase, APA PsycInfo, Web of Science, CINAHL, and Cochrane CENTRAL databases on relevant studies published up until 9 December 2024. EXPERT OPINION: Preliminary evidence supports the efficacy of ECT to treat depressive symptoms in patients with comorbid PTSD while there is more conflicting evidence for its use in patients with comorbid personality disorders, particularly borderline personality disorder. A careful exploration of trauma history, baseline mood symptoms, and previous treatment trials should be undertaken prior to the recommendation of ECT. Randomized controlled trials are needed to verify the therapeutic benefits of ECT for core symptom domains in other disorders.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.932
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0030.001
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.045
GPT teacher head0.380
Teacher spread0.335 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designOther design
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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