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Record W4413100073 · doi:10.1111/inm.70109

A Survey of 1144 <scp>ECT</scp> Recipients, Family Members and Friends: Does <scp>ECT</scp> Work?

2025· article· en· W4413100073 on OpenAlexaff
John Read, Lucy Johnstone, Sarah Price Hancock, Chris Harrop, Lisa Morrison, Sue Cunliffe

Bibliographic record

VenueInternational Journal of Mental Health Nursing · 2025
Typearticle
Languageen
FieldMedicine
TopicElectroconvulsive Therapy Studies
Canadian institutionsTraffic Injury Research Foundation
Fundersnot available
KeywordsPlaceboMoodAdverse effectDepression (economics)Quality of life (healthcare)PsychiatryMedicinePsychologyClinical trialClinical psychologyInternal medicineAlternative medicinePsychotherapist

Abstract

fetched live from OpenAlex

The last placebo-controlled ECT trial for depression occurred in 1985. While awaiting trials that meet today's standards of evidence-based medicine, this paper presents the responses, to an online survey, of 858 ECT recipients and 286 family members and friends, from 44 countries, on five effectiveness measures. The majority (55%-71%) reported either no benefit or a negative outcome on the five measures. The percentages reporting some benefit were: helped the specific problem for which ECT was given-45%; improved mood-41%; generally 'helpful'-41%; improved 'quality of life'-29%; reduced suicidality-33%. Respondents were, unusually, given the option, on four of these measures, to report that the variable had been made worse. The results were: specific problem made worse-37%; worse mood-29%; reduced quality of life-62%; and increased suicidality-19%. The findings were consistent with responses from family and friends. It is striking that nearly half (49%) reported that their quality of life was made 'much worse' (22%) or 'very much worse' (27%) by ECT. A partial explanation of this alarming outcome is that quality of life encompasses the adverse effects of ECT alongside any benefits. In conjunction with the absence of evidence that ECT is more effective than placebo, and the known long-term adverse effects on memory, these survey findings lead us to recommend a suspension of ECT in clinical settings pending independent large-scale placebo-controlled studies to determine whether ECT has any effectiveness relative to placebo, against which the many serious adverse effects can be weighed.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.263
Threshold uncertainty score0.868

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.361
Teacher spread0.340 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2025
Admission routes1
Has abstractyes

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